A nanofluidic-based enzymatic reaction on a chip

Takehiko Tsukahara, Eiichiro Tamaki, Akihide Hibara, Takehiko Kitamori

研究成果: Conference contribution

抄録

We report enzymatic reaction inside extended-nano spaces (101 - 102 nm) on a chip by using pressure-driven nanofludic control system. We examined the kinetic parameters of enzyme in the extended-nano spaces. The results showed that a first-order rate constant (kcat) for a nanospace was increased by a factor of about two compared with bulk and micro spaces. This is first observation of nanofluidic-based enzymatic reactions.

本文言語English
ホスト出版物のタイトルProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
編集者Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
出版社Chemical and Biological Microsystems Society
ページ1574-1576
ページ数3
ISBN(電子版)9780979806407
出版ステータスPublished - 2007
外部発表はい
イベント11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
継続期間: 2007 10 72007 10 11

出版物シリーズ

名前Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
国/地域France
CityParis
Period07/10/707/10/11

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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