A model system for studying superselective radiotherapy of lymph node metastasis in mice with swollen lymph nodes

Ryohei Kikuchi, Ariunbuyan Sukhbaatar, Maya Sakamoto, Shiro Mori, Tetsuya Kodama

研究成果: Article査読

抄録

Utilizing mice with swollen lymph nodes, we succeeded in irradiating individual metastatic lymph nodes through a hole in a lead shield. This system enabled us to increase the radiation dose to >8 Gy (the lethal dose for total-body irradiation) and evaluate both direct and abscopal antitumor effects.

本文言語English
ページ(範囲)53-57
ページ数5
ジャーナルClinical and Translational Radiation Oncology
20
DOI
出版ステータスPublished - 2020 1

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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