A microfludic device with interdigitated array electrodes for detection of hormone active chemicals using genetically-engineered yeast cells

Kosuke Ino, Yusuke Kitagawa, Hitoshi Shiku, Masahiro Koide, Yoshiko Horiguchi, Tomoaki Itayama, Tomoyuki Yasukawa, Tomokazu Matsue

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Endocrine disrupting chemicals that act like hormones is a potential hazard for human health. Therefore, it is necessary to develop a device that can detect easily hormone active chemicals. In this study, a microfludic device with some analytical chambers was fabricated for manipulating the yeast cells that were genetically engineered to respond to the presence of hormone active chemicals by synthesizing β-galactosidase (β-gal). Interdigitated array (IDA) electrodes with 40 electrode fingers were incorporated into the device for sensitive detection of the β-gal activity electrochemically, and hormone active chemicals were successfully detected by using the systems.

本文言語English
ホスト出版物のタイトルProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ1623-1625
ページ数3
ISBN(印刷版)9780979806421
出版ステータスPublished - 2009 1 1
イベント13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
継続期間: 2009 11 12009 11 5

出版物シリーズ

名前Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
国/地域Korea, Republic of
CityJeju
Period09/11/109/11/5

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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