A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells

T. Wagner, R. Molina, M. Biselli, M. Canzoneri, T. Schnitzler, T. Yoshinobu, M. J. Scheming

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

The metabolic activity of cells can be utilised to indicate the general reaction of them towards the cell environment. Hence, the influence of a specific reagent (e.g., drugs, toxins, growth factors, etc.) in the cell-culture medium can be determined by recording the metabolic activity. The light-addressable potentiometric sensor (LAPS), a field-effect-based chemical sensor, provides a promising technology platform to record the metabolic activity of cells with a spatial resolution. In this work, a portable LAPS device will be introduced which is capable of measuring at 16 different locations within the sensor surface simultaneously. The cultivation and recording of the metabolic activity of CHO (Chinese hamster ovary) cells within the LAPS set-up will be demonstrated.

本文言語English
ホスト出版物のタイトルTRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems
ページ1107-1110
ページ数4
DOI
出版ステータスPublished - 2007
イベント4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07 - Lyon, France
継続期間: 2007 6 102007 6 14

出版物シリーズ

名前TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems

Other

Other4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07
国/地域France
CityLyon
Period07/6/1007/6/14

ASJC Scopus subject areas

  • 制御およびシステム工学
  • 電子工学および電気工学

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