A large, square-shaped, DNA origami nanopore with sealing function on a giant vesicle membrane

研究成果: Article査読

抄録

Intaking molecular information from the external environment is essential for the normal functioning of artificial cells/molecular robots. Herein, we report the design and function of a membrane nanopore using a DNA origami square tube with a cross-section of 100 nm2. When the nanopore is added to a giant vesicle that mimics a cell membrane, the permeation of large external hydrophilic fluorescent molecules is observed. Furthermore, the addition of up to four ssDNA strands enables size-based selective transport of molecules. A controllable artificial nanopore should facilitate the communication between the vesicle components and their environment.

本文言語English
ページ(範囲)2990-2993
ページ数4
ジャーナルChemical Communications
57
24
DOI
出版ステータスPublished - 2021 3 25

ASJC Scopus subject areas

  • 触媒
  • 電子材料、光学材料、および磁性材料
  • セラミックおよび複合材料
  • 化学 (全般)
  • 表面、皮膜および薄膜
  • 金属および合金
  • 材料化学

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