TY - JOUR
T1 - A concise synthetic approach to β,γ-dehydrocurvularin
T2 - Synthesis of (±)-di-O-methyl-β,γ-dehydrocurvularin
AU - Miyagi, Takuho
AU - Kuwahara, Shigefumi
N1 - Funding Information:
This work was financially supported, in part, by grant-aid for scientific research (B) from the Ministry of
Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2007
Y1 - 2007
N2 - A concise synthesis of di-O-methyl-β,γ-dehydrocurvularin, the di-O-methylated derivative of the naturally occurring nematicidal macrolide, β,γ-dehydrocurvuralin, was accomplished by starting from a commercially available aromatic carboxylic acid in a three-step sequence consisting of esterification, Friedel-Crafts acylation, and microwave-promoted ring-closing metathesis.
AB - A concise synthesis of di-O-methyl-β,γ-dehydrocurvularin, the di-O-methylated derivative of the naturally occurring nematicidal macrolide, β,γ-dehydrocurvuralin, was accomplished by starting from a commercially available aromatic carboxylic acid in a three-step sequence consisting of esterification, Friedel-Crafts acylation, and microwave-promoted ring-closing metathesis.
KW - Curvuralin
KW - Macrolide
KW - Microwave-promoted reaction
KW - Nematicide
KW - Ring-closing metathesis
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U2 - 10.1271/bbb.70094
DO - 10.1271/bbb.70094
M3 - Article
C2 - 17587698
AN - SCOPUS:34347356642
SN - 0916-8451
VL - 71
SP - 1592
EP - 1594
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
IS - 6
ER -