TY - JOUR
T1 - A case of phaeohyphomycosis infected with Exophiala jeanselmei
AU - Okada, Shuko
AU - Masu, Takashi
AU - Tsunoda, Takahiko
AU - Kawasaki, Masako
AU - Mochizuki, Takashi
AU - Okuyama, Ryuhei
AU - Aiba, Setsuya
PY - 2007
Y1 - 2007
N2 - A 77-year-old Japanese man presented with an asymptomatic tumor affecting the dorsum of the right hand. He had been treated for double cancer in the prostate and lung associated with multiple metastases. On examination, there was an elastic hard tumor in the subcutaneous tissue with limited mobility. Excisional biopsy showed that the tumor included yellowish white-colored atheromatous materials, from which fungus was detected in the culture. Histopathologically, there were numerous spores and hyphae with PAS positive stain within granulomas. Based on a molecular biologically technique, type 6 of Exophiala jeanselmei was identified from the tumor. To our knowledge, only one case of phaeohyphomycosis infected with Exophiala jeanselmei has been reported in the northeast area of Japan. The solitary tumor in our case is reminiscent of more common skin diseases such as epidermal cyst. However, for proper diagnosis and therapy, we should not neglect the possibility of fungal infection in cases of compromised hosts.
AB - A 77-year-old Japanese man presented with an asymptomatic tumor affecting the dorsum of the right hand. He had been treated for double cancer in the prostate and lung associated with multiple metastases. On examination, there was an elastic hard tumor in the subcutaneous tissue with limited mobility. Excisional biopsy showed that the tumor included yellowish white-colored atheromatous materials, from which fungus was detected in the culture. Histopathologically, there were numerous spores and hyphae with PAS positive stain within granulomas. Based on a molecular biologically technique, type 6 of Exophiala jeanselmei was identified from the tumor. To our knowledge, only one case of phaeohyphomycosis infected with Exophiala jeanselmei has been reported in the northeast area of Japan. The solitary tumor in our case is reminiscent of more common skin diseases such as epidermal cyst. However, for proper diagnosis and therapy, we should not neglect the possibility of fungal infection in cases of compromised hosts.
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U2 - 10.2336/nishinihonhifu.69.162
DO - 10.2336/nishinihonhifu.69.162
M3 - Article
AN - SCOPUS:34248663530
VL - 69
SP - 162
EP - 164
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
SN - 0386-9784
IS - 2
ER -