TY - JOUR
T1 - A case of Marchiafava-Bignami disease with complete recovery
T2 - Sequential imaging documenting improvement of callosal lesions
AU - Tobita, Muneshige
AU - Mochizuki, Hiroshi
AU - Takahashi, Shoki
AU - Onodera, Hiroshi
AU - Itoyama, Yasuto
AU - Iwasaki, Yuzo
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1997/6
Y1 - 1997/6
N2 - Serial CT and MR imaging findings in a 44-year-old woman with Marchiafava-Bignami disease (MBD) are reported. In the acute stage, CT studies disclosed subtle hypodensity in the splenium, and T2-weighted MR images revealed apparent high signal intensity of the splenium and the central portion of the corpus callosum. Treatment with vitamin B complex resulted in complete recovery. T2-weighted MR images obtained three weeks after admission revealed dramatic resolution of imaging abnormalities, with only faint high signal intensity remaining in the splenium. The sequential changes observed on CT and MR images provided early diagnosis of MBD and the resolution of the lesion considered as brain edema, which suggested that edema might, in addition to demyelination or necrosis, be involved in the acute progression of MBD.
AB - Serial CT and MR imaging findings in a 44-year-old woman with Marchiafava-Bignami disease (MBD) are reported. In the acute stage, CT studies disclosed subtle hypodensity in the splenium, and T2-weighted MR images revealed apparent high signal intensity of the splenium and the central portion of the corpus callosum. Treatment with vitamin B complex resulted in complete recovery. T2-weighted MR images obtained three weeks after admission revealed dramatic resolution of imaging abnormalities, with only faint high signal intensity remaining in the splenium. The sequential changes observed on CT and MR images provided early diagnosis of MBD and the resolution of the lesion considered as brain edema, which suggested that edema might, in addition to demyelination or necrosis, be involved in the acute progression of MBD.
KW - Alcoholism
KW - CT
KW - Corpus callosum
KW - MRI
KW - Marchiafava-Bignami disease
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U2 - 10.1620/tjem.182.175
DO - 10.1620/tjem.182.175
M3 - Article
C2 - 9261936
AN - SCOPUS:0030866416
VL - 182
SP - 175
EP - 179
JO - Tohoku Journal of Experimental Medicine
JF - Tohoku Journal of Experimental Medicine
SN - 0040-8727
IS - 2
ER -