Takahiro Eitsuka

2021

Ethanolamine Plasmalogen Suppresses Apoptosis in Human Intestinal Tract Cells in Vitro by Attenuating Induced Inflammatory Stress

Nguma, E., Yamashita, S., Kumagai, K., Otoki, Y., Yamamoto, A., Eitsuka, T., Nakagawa, K., Miyazawa, T. & Kinoshita, M., 2021 2月 2, In: ACS Omega. 6, 4, p. 3140-3148 9 p.

研究成果: Article › 査読

Open Access

6 被引用数 (Scopus)

2020

Analysis of oxidation products of α-tocopherol in extra virgin olive oil using liquid chromatography–tandem mass spectrometry

Tanno, R., Kato, S., Shimizu, N., Ito, J., Sato, S., Ogura, Y., Sakaino, M., Sano, T., Eitsuka, T., Kuwahara, S., Miyazawa, T. & Nakagawa, K., 2020 2月 15, In: Food Chemistry. 306, 125582.

研究成果: Article › 査読

9 被引用数 (Scopus)

Efficient immortalization of human dental pulp stem cells with expression of cell cycle regulators with the intact chromosomal condition

Orimoto, A., Kyakumoto, S., Eitsuka, T., Nakagawa, K., Kiyono, T. & Fukuda, T., 2020, In: PloS one. 15, 3, e0229996.

研究成果: Article › 査読

Open Access

9 被引用数 (Scopus)

Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor

Fukuda, T., Takahashi, K., Takase, S., Orimoto, A., Eitsuka, T., Nakagawa, K. & Kiyono, T., 2020 3月 18, In: Frontiers in Cell and Developmental Biology. 8, 157.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Intestinal Absorption and Tissue Distribution of Aza-Sugars from Mulberry Leaves and Evaluation of Their Transport by Sugar Transporters

Takasu, S., Parida, I. S., Ito, J., Kojima, Y., Eitsuka, T., Kimura, T. & Nakagawa, K., 2020 6月 17, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6656-6663 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Primary and immortalized cell lines derived from the Amami rabbit (Pentalagus furnessi) and evolutionally conserved cell cycle control with CDK4 and Cyclin D1

Orimoto, A., Katayama, M., Tani, T., Ito, K., Eitsuka, T., Nakagawa, K., Inoue-Murayama, M., Onuma, M., Kiyono, T. & Fukuda, T., 2020 5月 14, In: Biochemical and biophysical research communications. 525, 4, p. 1046-1053 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Structural changes of ethanolamine plasmalogen during intestinal absorption

Takahashi, T., Kamiyoshihara, R., Otoki, Y., Ito, J., Kato, S., Suzuki, T., Yamashita, S., Eitsuka, T., Ikeda, I. & Nakagawa, K., 2020 9月, In: Food and Function. 11, 9, p. 8068-8076 9 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Supplementation of: Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

Parida, I. S., Takasu, S., Ito, J., Ikeda, R., Yamagishi, K., Kimura, T., Eitsuka, T. & Nakagawa, K., 2020 5月, In: Food and Function. 11, 5, p. 3926-3940 15 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

2019

Comparison of blood profiles of γ-Oryzanol and ferulic acid in rats after oral intake of γ-Oryzanol

Kokumai, T., Ito, J., Kobayashi, E., Shimizu, N., Hashimoto, H., Eitsuka, T., Miyazawa, T. & Nakagawa, K., 2019 5月, In: Nutrients. 11, 5, 1174.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Definitive evidence of the presence of 24-methylenecycloartanyl ferulate and 24-methylenecycloartanyl caffeate in barley

Ito, J., Sawada, K., Ogura, Y., Xinyi, F., Rahmania, H., Mohri, T., Kohyama, N., Kwon, E., Eitsuka, T., Hashimoto, H., Kuwahara, S., Miyazawa, T. & Nakagawa, K., 2019 12月 1, In: Scientific reports. 9, 1, 12572.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Evaluation of squalene oxidation mechanisms in human skin surface lipids and shark liver oil supplements

Shimizu, N., Ito, J., Kato, S., Eitsuka, T., Saito, T., Nishida, H., Miyazawa, T. & Nakagawa, K., 2019 12月 1, In: Annals of the New York Academy of Sciences. 1457, 1, p. 158-165 8 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Evaluation of γ-oryzanol accumulation and lipid metabolism in the body of mice following long-term administration of γ-oryzanol

Kobayashi, E., Ito, J., Shimizu, N., Kokumai, T., Kato, S., Sawada, K., Hashimoto, H., Eitsuka, T., Miyazawa, T. & Nakagawa, K., 2019 1月, In: Nutrients. 11, 1, 104.

研究成果: Article › 査読

11 被引用数 (Scopus)

Extended proliferation of chicken- and Okinawa rail-derived fibroblasts by expression of cell cycle regulators

Katayama, M., Kiyono, T., Ohmaki, H., Eitsuka, T., Endoh, D., Inoue-Murayama, M., Nakajima, N., Onuma, M. & Fukuda, T., 2019 5月, In: Journal of Cellular Physiology. 234, 5, p. 6709-6720 12 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Human-derived corneal epithelial cells expressing cell cycle regulators as a new resource for in vitro ocular toxicity testing

Fukuda, T., Gouko, R., Eitsuka, T., Suzuki, R., Takahashi, K., Nakagawa, K., Sugano, E., Tomita, H. & Kiyono, T., 2019, In: Frontiers in Genetics. 10, JUN, 587.

研究成果: Article › 査読

Open Access

8 被引用数 (Scopus)

Physiological effects and organ distribution of bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in C57BL/6J mice

Parida, I. S., Takasu, S., Ito, J., Ikeda, R., Yamagishi, K., Kimura, T., Miyazawa, T., Eitsuka, T. & Nakagawa, K., 2019, In: Journal of nutritional science and vitaminology. 65, 2, p. 157-163 7 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Significance of squalene in rice bran oil and perspectives on squalene oxidation

Shimizu, N., Ito, J., Kato, S., Eitsuka, T., Miyazawa, T. & Nakagawa, K., 2019, In: Journal of nutritional science and vitaminology. 65, p. S62-S66

研究成果: Article › 査読

Open Access

13 被引用数 (Scopus)

The Adjuvant Effect of Squalene, an Active Ingredient of Functional Foods, on Doxorubicin-Treated Allograft Mice

Narayan Bhilwade, H., Tatewaki, N., Konishi, T., Nishida, M., Eitsuka, T., Yasui, H., Inanami, O., Handa, O., Naito, Y., Ikekawa, N. & Nishida, H., 2019, In: Nutrition and Cancer. 71, 7, p. 1153-1164 12 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

The differential cellular uptake of curcuminoids in vitro depends dominantly on albumin interaction

Itaya, M., Miyazawa, T., Zingg, J. M., Eitsuka, T., Azzi, A., Meydani, M., Miyazawa, T. & Nakagawa, K., 2019 6月, In: Phytomedicine. 59, 152902.

研究成果: Article › 査読

6 被引用数 (Scopus)

2018

Absorption and Metabolism of Luteolin in Rats and Humans in Relation to in Vitro Anti-inflammatory Effects

Hayasaka, N., Shimizu, N., Komoda, T., Mohri, S., Tsushida, T., Eitsuka, T., Miyazawa, T. & Nakagawa, K., 2018 10月 31, In: Journal of Agricultural and Food Chemistry. 66, 43, p. 11320-11329 10 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

Determination of triacylglycerol oxidation mechanisms in canola oil using liquid chromatography–tandem mass spectrometry

Kato, S., Shimizu, N., Hanzawa, Y., Otoki, Y., Ito, J., Kimura, F., Takekoshi, S., Sakaino, M., Sano, T., Eitsuka, T., Miyazawa, T. & Nakagawa, K., 2018, In: npj Science of Food. 2, 1, 1.

研究成果: Article › 査読

Open Access

35 被引用数 (Scopus)

Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant CDK4, Cyclin D1, and telomerase reverse transcriptase

Gouko, R., Onuma, M., Eitsuka, T., Katayama, M., Takahashi, K., Nakagawa, K., Inoue-Murayama, M., Kiyono, T. & Fukuda, T., 2018 12月 1, In: Cytotechnology. 70, 6, p. 1619-1630 12 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta)

Fukuda, T., Eitsuka, T., Donai, K., Kurita, M., Saito, T., Okamoto, H., Kinoshita, K., Katayama, M., Nitto, H., Uchida, T., Onuma, M., Sone, H., Inoue-Murayama, M. & Kiyono, T., 2018 12月 1, In: Scientific reports. 8, 1, 9229.

研究成果: Article › 査読

Open Access

9 被引用数 (Scopus)

Oxidation of squalene by singlet oxygen and free radicals results in different compositions of squalene monohydroperoxide isomers

Shimizu, N., Ito, J., Kato, S., Otoki, Y., Goto, M., Eitsuka, T., Miyazawa, T. & Nakagawa, K., 2018 12月 1, In: Scientific reports. 8, 1, 9116.

研究成果: Article › 査読

Open Access

19 被引用数 (Scopus)

2017

Expression of Six Proteins Causes Reprogramming of Porcine Fibroblasts Into Induced Pluripotent Stem Cells With Both Active X Chromosomes

Fukuda, T., Tani, T., Haraguchi, S., Donai, K., Nakajima, N., Uenishi, H., Eitsuka, T., Miyagawa, M., Song, S., Onuma, M., Hoshino, Y., Sato, E. & Honda, A., 2017 3月 1, In: Journal of Cellular Biochemistry. 118, 3, p. 537-553 17 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

High purity tocotrienols attenuate atherosclerotic lesion formation in apoE-KO mice

Shibata, A., Kobayashi, T., Asai, A., Eitsuka, T., Oikawa, S., Miyazawa, T. & Nakagawa, K., 2017 10月, In: Journal of Nutritional Biochemistry. 48, p. 44-50 7 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Mass spectrometric discrimination of squalene monohydroperoxide isomers

Shimizu, N., Bersabe, H., Ito, J., Kato, S., Towada, R., Eitsuka, T., Kuwahara, S., Miyazawa, T. & Nakagawa, K., 2017, In: Journal of oleo science. 66, 3, p. 227-234 8 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

2016

A combination of δ-tocotrienol and ferulic acid synergistically inhibits telomerase activity in DLD-1 human colorectal adenocarcinoma cells

Eitsuka, T., Tatewaki, N., Nishida, H., Nakagawa, K. & Miyazawa, T., 2016, In: Journal of nutritional science and vitaminology. 62, 5, p. 281-287 7 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Cellular conservation of endangered midget buffalo (Lowland Anoa, Bubalus quarlesi) by establishment of primary cultured cell, and its immortalization with expression of cell cycle regulators

Fukuda, T., Iino, Y., Eitsuka, T., Onuma, M., Katayama, M., Murata, K., Inoue-Murayama, M., Hara, K., Isogai, E. & Kiyono, T., 2016 10月 1, In: Cytotechnology. 68, 5, p. 1937-1947 11 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Establishment of an immortalized cell line derived from the prairie vole via lentivirus-mediated transduction of mutant cyclin-dependent kinase 4, cyclin d, and telomerase reverse transcriptase

Katayama, M., Kiyono, T., Horie, K., Hirayama, T., Eitsuka, T., Kuroda, K., Donai, K., Hidema, S., Nishimori, K. & Fukuda, T., 2016 2月 14, In: Experimental Animals. 65, 1, p. 87-96 10 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Squalene inhibits ATM-dependent signaling in γiR-induced DNA damage response through induction of Wip1 phosphatase

Tatewaki, N., Konishi, T., Nakajima, Y., Nishida, M., Saito, M., Eitsuka, T., Sakamaki, T., Ikekawa, N. & Nishida, H., 2016 1月 1, In: PloS one. 11, 1, 0147570.

研究成果: Article › 査読

12 被引用数 (Scopus)

The fruit of Acanthopanax senticosus (Rupr. et Maxim.) Harms improves insulin resistance and hepatic lipid accumulation by modulation of liver adenosine monophosphate–activated protein kinase activity and lipogenic gene expression in high-fat diet–fed obese mice

Saito, T., Nishida, M., Saito, M., Tanabe, A., Eitsuka, T., Yuan, S. H., Ikekawa, N. & Nishida, H., 2016 10月 1, In: Nutrition Research. 36, 10, p. 1090-1097 8 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation: Via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling

Burdeos, G. C., Ito, J., Eitsuka, T., Nakagawa, K., Kimura, F. & Miyazawa, T., 2016 10月 1, In: Food and Function. 7, 10, p. 4170-4174 5 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

2015

Establishment of cell lines derived from the genus macaca through controlled expression of cell cycle regulators

Kuroda, K., Kiyono, T., Eitsuka, T., Isogai, H., Takahashi, K., Donai, K., Isogai, E. & Fukuda, T., 2015 2月, In: Journal of Cellular Biochemistry. 116, 2, p. 205-211 7 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Metabolism and cytotoxic effects of phosphatidylcholine hydroperoxide in human hepatoma HepG2 cells

Suzuki, Y., Nakagawa, K., Kato, S., Tatewaki, N., Mizuochi, S., Ito, J., Eitsuka, T., Nishida, H. & Miyazawa, T., 2015 3月 20, In: Biochemical and biophysical research communications. 458, 4, p. 920-927 8 p., 33455.

研究成果: Article › 査読

3 被引用数 (Scopus)

2014

Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase

Donai, K., Kiyono, T., Eitsuka, T., Guo, Y., Kuroda, K., Sone, H., Isogai, E. & Fukuda, T., 2014 4月 20, In: Journal of Biotechnology. 176, 1, p. 50-57 8 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Synergistic inhibition of cancer cell proliferation with a combination of δ-tocotrienol and ferulic acid

Eitsuka, T., Tatewaki, N., Nishida, H., Kurata, T., Nakagawa, K. & Miyazawa, T., 2014 10月 24, In: Biochemical and biophysical research communications. 453, 3, p. 606-611 6 p.

研究成果: Article › 査読

46 被引用数 (Scopus)

2012

Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells

Eitsuka, T., Nakagawa, K., Ono, Y., Tatewaki, N., Nishida, H., Kurata, T., Shoji, N. & Miyazawa, T., 2012 7月 30, In: FEBS Letters. 586, 16, p. 2542-2547 6 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Efficient establishment of pig embryonic fibroblast cell lines with conditional expression of the simian vacuolating virus 40 large T fragment

Fukuda, T., Katayama, M., Yoshizawa, T., Eitsuka, T., Mizukami, H., Nakagawa, K., Ito, H., Komagata, H., Song, S., Roh, S., Hoshino, Y., Sato, E., Hanada, H., Nishimori, K., Miyazawa, T. & Uchida, T., 2012, In: Bioscience, Biotechnology and Biochemistry. 76, 7, p. 1372-1377 6 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Non-thermal DNA damage of cancer cells using near-infrared irradiation

Tanaka, Y., Tatewaki, N., Nishida, H., Eitsuka, T., Ikekawa, N. & Nakayama, J., 2012 8月, In: Cancer science. 103, 8, p. 1467-1473 7 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

2006

Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol

Eitsuka, T., Nakagawa, K. & Miyazawa, T., 2006 9月 15, In: Biochemical and biophysical research communications. 348, 1, p. 170-175 6 p.

研究成果: Article › 査読

84 被引用数 (Scopus)

2005

Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerases I and II

Yonezawa, Y., Tsuzuki, T., Eitsuka, T., Miyazawa, T., Hada, T., Uryu, K., Murakami-Nakai, C., Ikawa, H., Kuriyama, I., Takemura, M., Oshige, M., Yoshida, H., Sakaguchi, K. & Mizushina, Y., 2005 3月 1, In: Archives of Biochemistry and Biophysics. 435, 1, p. 197-206 10 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation

Yonezawa, Y., Hada, T., Uryu, K., Tsuzuki, T., Eitsuka, T., Miyazawa, T., Murakami-Nakai, C., Yoshida, H. & Mizushina, Y., 2005 8月 1, In: Biochemical Pharmacology. 70, 3, p. 453-460 8 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Polyunsaturated fatty acids inhibit telomerase activity in DLD-1 human colorectal adenocarcinoma cells: A dual mechanism approach

Eitsuka, T., Nakagawa, K., Suzuki, T. & Miyazawa, T., 2005 10月 15, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1737, 1, p. 1-10 10 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

2004

DNA chip analysis of comprehensive food function: Inhibition of angiogenesis and telomerase activity with unsaturated vitamin E, tocotrienol

Nakagawa, K., Eitsuka, T., Inokuchi, H. & Miyazawa, T., 2004 1月 1, In: BioFactors. 21, 1-4, p. 5-10 6 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Dual mechanisms for telomerase inhibition in DLD-1 human colorectal adenocarcinoma cells by polyunsaturated fatty acids

Eitsuka, T., Nakagawa, K. & Miyazawa, T., 2004 1月 1, In: BioFactors. 21, 1-4, p. 19-21 3 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Inhibitory action of conjugated C₁₈-fatty acids on DNA polymerases and DNA topoisomerases

Mizushina, Y., Tsuzuki, T., Eitsuka, T., Miyazawa, T., Kobayashi, K., Ikawa, H., Kuriyama, I., Yonezawa, Y., Takemura, M., Yoshida, H. & Sakaguchi, K., 2004 10月, In: Lipids. 39, 10, p. 977-983 7 p., L9577.

研究成果: Article › 査読

14 被引用数 (Scopus)

Telomerase inhibition by sulfoquinovosyldiacylglycerol from edible purple laver (Porphyra yezoensis)

Eitsuka, T., Nakagawa, K., Igarashi, M. & Miyazawa, T., 2004 8月 20, In: Cancer Letters. 212, 1, p. 15-20 6 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

永塚 貴弘

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永塚貴弘