Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum

Yi Bing Wu, Zhi Yu Ni, Chang Hong Huo, Jian Su, Mei Dong, Françoise Sauriol, Qing Wen Shi, Yu Cheng Gu, Hiromasa Kiyota

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H, 13CNMR, DEPT, 1H-1H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).

Original languageEnglish
Pages (from-to)736-740
Number of pages5
JournalBioscience, Biotechnology and Biochemistry
Volume77
Issue number4
DOIs
Publication statusPublished - 2013 Jun 14

Keywords

  • Limonoid
  • Mexicanolide
  • NMR
  • Structural elucidation
  • Xylocarpus granatum

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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