X-ray phase imaging: From synchrotron to hospital

Atsushi Momose, Wataru Yashiro, Kazuhiro Kido, Junko Kiyohara, Chiho Makifuchi, Tsukasa Ito, Sumiya Nagatsuka, Chika Honda, Daiji Noda, Tadashi Hattori, Tokiko Endo, Masabumi Nagashima, Junji Tanaka

Research output: Contribution to journalArticlepeer-review

88 Citations (Scopus)


With the aim of clinical applications of X-ray phase imaging based on TalbotLau-type grating interferometry to joint diseases and breast cancer, machines employing a conventional X-ray generator have been developed and installed in hospitals. The machine operation especially for diagnosing rheumatoid arthritis is described, which relies on the fact that cartilage in finger joints can be depicted with a dose of several milligray. The palm of a volunteer observed with 19 s exposure (total scan time: 32 s) is reported with a depicted cartilage feature in joints. This machine is now dedicated for clinical research with patients.

Original languageEnglish
JournalPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Issue number2010
Publication statusPublished - 2014 Mar 6


  • Clinics
  • Grating interferometry
  • Phase contrast
  • X-ray

ASJC Scopus subject areas

  • Mathematics(all)
  • Engineering(all)
  • Physics and Astronomy(all)


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