TY - JOUR
T1 - WoLF PSORT
T2 - Protein localization predictor
AU - Horton, Paul
AU - Park, Keun Joon
AU - Obayashi, Takeshi
AU - Fujita, Naoya
AU - Harada, Hajime
AU - Adams-Collier, C. J.
AU - Nakai, Kenta
N1 - Funding Information:
KN was partly supported by a grant from the National Project on Protein Structural and Functional Analyses by the Ministry of Education, Culture, Sports, Science and Technology in Japan. The annual budget of the Human Genome Center was used for the publication of this paper.
PY - 2007/7
Y1 - 2007/7
N2 - WoLF PSORT is an extension of the PSORT II program for protein subcellular location prediction. WoLF PSORT converts protein amino acid sequences into numerical localization features; based on sorting signals, amino acid composition and functional motifs such as DNA-binding motifs. After conversion, a simple k-nearest neighbor classifier is used for prediction. Using html, the evidence for each prediction is shown in two ways: (i) a list of proteins of known localization with the most similar localization features to the query, and (ii) tables with detailed information about individual localization features. For convenience, sequence alignments of the query to similar proteins and links to UniProt and Gene Ontology are provided. Taken together, this information allows a user to understand the evidence (or lack thereof) behind the predictions made for particular proteins. WoLF PSORT is available at wolfpsort.org.
AB - WoLF PSORT is an extension of the PSORT II program for protein subcellular location prediction. WoLF PSORT converts protein amino acid sequences into numerical localization features; based on sorting signals, amino acid composition and functional motifs such as DNA-binding motifs. After conversion, a simple k-nearest neighbor classifier is used for prediction. Using html, the evidence for each prediction is shown in two ways: (i) a list of proteins of known localization with the most similar localization features to the query, and (ii) tables with detailed information about individual localization features. For convenience, sequence alignments of the query to similar proteins and links to UniProt and Gene Ontology are provided. Taken together, this information allows a user to understand the evidence (or lack thereof) behind the predictions made for particular proteins. WoLF PSORT is available at wolfpsort.org.
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U2 - 10.1093/nar/gkm259
DO - 10.1093/nar/gkm259
M3 - Article
C2 - 17517783
AN - SCOPUS:34547560275
SN - 0305-1048
VL - 35
SP - W585-W587
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - SUPPL.2
ER -