This paper describes wireless biotelemetry system implementation in order to improve the flexibility of existing tele-cardiac monitoring system. The proposed method is an integration of single-lead ECG front end circuit and TCP/IP based wireless communication System on Chip (SoC) running 3 parallel tasks including modified Amplitude Zone Time-Epoch Coding (AZTEC) data reduction algorithm. The electrode wireless node is designed to minimize the size and power consumption meanwhile maintaining acceptable performance of the instrument. On the other hand, an ECG server is implemented as a TCP/IP data receiving unit featuring data recovery algorithm with store and forward capability. This feature has enabled integration with existing tele-cardiac monitoring system, in addition to raw ECG data logging for manual analysis. The experiment has demonstrated the implementation feasibility of ECG acquisition system with commercial ECG front-end IC and an on-chip ADC. A moderate performance and acceptable error have been observed. The proposed system provides a potential improvement in telemedicine service.