Widely Spread Unilateral Inflammatory Linear Verrucous Epidermal Nevus (ILVEN)

Kayo Tanita, Taku Fujimura, Yota Sato, Chunbing Lyu, Setsuya Aiba

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Inflammatory linear verrucous epidermal nevus (ILVEN) is an epidermal nevus that clinically and histologically mimics linear psoriasis. The pathogenesis of psoriasis has been widely investigated, with recent studies focusing especially on targeting proinflammatory cytokines such as IL-17A, TNFα, IL-23, and IL-12, while little is known about ILVEN. Since the treatment for ILVEN varies widely from the administration of topical ointment for psoriasis to invasive methods such as carbon dioxide gas laser, the differential diagnosis between ILVEN and psoriasis is necessary. In this report, we describe a case of widely spread unilateral ILVEN that clinically and histologically mimicked psoriasis vulgaris and could be diagnosed by immunohistochemical staining focused on the IL-36γ/IL-17A axis.

Original languageEnglish
Pages (from-to)170-175
Number of pages6
JournalCase Reports in Dermatology
Volume10
Issue number2
DOIs
Publication statusPublished - 2018 May 1
Externally publishedYes

Keywords

  • Differential diagnosis
  • IL-17
  • IL-36Iγ
  • ILVEN
  • Inflammatory linear verrucous epidermal nevus
  • Psoriasis

ASJC Scopus subject areas

  • Dermatology

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