What does the fruitless gene tell us about nature vs. nurture in the sex life of Drosophila?

Daisuke Yamamoto, Soh Kohatsu

    Research output: Contribution to journalReview articlepeer-review

    4 Citations (Scopus)

    Abstract

    The fruitless (fru) gene in Drosophila has been proposed to play a master regulator role in the formation of neural circuitries for male courtship behavior, which is typically considered to be an innate behavior composed of a fixed action pattern as generated by the central pattern generator. However, recent studies have shed light on experience-dependent changes and sensory-input-guided plasticity in courtship behavior. For example, enhanced male-male courtship, a fru mutant “hallmark,” disappears when fru-mutant males are raised in isolation. The fact that neural fru expression is induced by neural activities in the adult invites the supposition that Fru as a chromatin regulator mediates experience-dependent epigenetic modification, which underlies the neural and behavioral plasticity.

    Original languageEnglish
    Pages (from-to)139-147
    Number of pages9
    JournalFly
    Volume11
    Issue number2
    DOIs
    Publication statusPublished - 2017 Apr 3

    Keywords

    • Or47b
    • behavioral plasticity
    • courtship
    • fruitless
    • olfaction
    • vision

    ASJC Scopus subject areas

    • Insect Science

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