West Nile virus: Understanding its past, present, and future

Yusuke Sayama, Tetsuya Mizutani

Research output: Contribution to journalReview articlepeer-review


The West Nile virus (WNV) is a mosquito-borne flavivirus that causes significant morbidity and mortality in birds, horses, and humans. WNV-infection causes clinical symptoms such as WNV fever to fatal meningoencephalitis in humans. The emergence and spread of WNV from North America to South America during the last decade and the recent outbreaks of this disease in both humans and horses in Europe suggest that its epidemiology of infection is evolving. This review will present an overview of WNV virology, vaccine development, and practical aspects of reducing risk of a possible WNV invasion in Japan.

Original languageEnglish
Pages (from-to)413-420
Number of pages8
JournalJournal of Disaster Research
Issue number4
Publication statusPublished - 2011 Aug


  • Diagnosis
  • Mosquito-borne flavivirus
  • Outbreakes
  • Vaccine development
  • West Nile virus

ASJC Scopus subject areas

  • Safety, Risk, Reliability and Quality
  • Engineering (miscellaneous)


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