Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis: Polymer-supported glycosyl donor

S. Manabe, Y. Ito

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.

Original languageEnglish
Pages (from-to)1234-1235
Number of pages2
JournalChemical and Pharmaceutical Bulletin
Volume49
Issue number9
DOIs
Publication statusPublished - 2001

Keywords

  • Linker
  • Oligosaccharide
  • Solid-phase synthesis

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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