Voltage-dependent anion channels: Their roles in plant defense and cell death

Tomonobu Kusano, Chika Tateda, Yoshihiro Takahashi, Thomas Berberich

    Research output: Contribution to journalArticlepeer-review

    41 Citations (Scopus)

    Abstract

    Thevoltage-dependentanionchannels(VDACs), mitochondrial outer membrane components, are present in organisms from fungi to animals and plants. They are thought to function in the regulation of metabolite transport between mitochondria and the cytoplasm. Sufficient knowledge on plant VDACs has been accumulated, so that we can here summarize the current information. Then, the involvement of mitochondria in plant defense and cell death is overviewed. While, in mammals, it is suggested that VDAC, also known as a component of the permeability transition pore (PTP) complex formed in the junction site of mitochondrial outer and inner membrane, is a key player in mitochondria-mediated cell death, little is known about the role of plant VDACs in this process. We have shown that plant VDACs are involved in mitochondria-mediated cell death and in defense against a non-host pathogen. In light of the current findings, we discuss the role of the PTP complex and VDAC as its component in plant pathogen defense and cell death.

    Original languageEnglish
    Pages (from-to)1301-1308
    Number of pages8
    JournalPlant Cell Reports
    Volume28
    Issue number9
    DOIs
    Publication statusPublished - 2009 Aug

    Keywords

    • Bax Cell death Defense Mitochondrion Plant VDAC

    ASJC Scopus subject areas

    • Agronomy and Crop Science
    • Plant Science

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