Virilizing ovarian dermoid cyst with peripheral steroid cells: A case study with immunohistochemical study of steroidogenesis

Françoise Boman, Marie Christine Vantyghem, Denis Querleu, Hironobu Sasano

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A case of virilizing ovarian dermoid cyst with peripheral steroid cells and virilization is reported in a 62-year-old woman. The level of testosterone dropped to normal after oophorectomy. The cyst wall was bordered by a discontinuous band of steroid cells focally accompanied by smooth muscle cells. Immunohistochemically, the steroid cells were enzymatically active and displayed a profile similar to the internal theca cells of ovarian follicles. These steroid cells were most probably modified stromal cells associated with smooth muscle metaplasia of the ovarian stroma.

Original languageEnglish
Pages (from-to)174-177
Number of pages4
JournalInternational Journal of Gynecological Pathology
Volume18
Issue number2
DOIs
Publication statusPublished - 1999 Apr

Keywords

  • Dermoid cyst
  • Hilus cells
  • Immunohistochemistry
  • Leydig cells
  • Lutein cells
  • Steroid cells
  • Steroidogenesis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynaecology

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