Versatile synthesis of benzothiophenes and benzoselenophenes by rapid assembly of arylzinc reagents, alkynes, and elemental chalcogens

Research output: Contribution to journalArticlepeer-review

85 Citations (Scopus)

Abstract

Rapidly aSSembled: The combination of cobalt-catalyzed migratory arylzincation and copper-mediated/catalyzed chalcogenative cyclization allows the construction of benzothiophenes and benzoselenophenes from arylzinc reagents, alkynes, and elemental chalcogens. Benzothiophenes and benzoselenophenes diversely functionalized at the benzene ring moiety can be prepared, which are not readily accessible by conventional methods.

Original languageEnglish
Pages (from-to)10496-10499
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number40
DOIs
Publication statusPublished - 2013 Sep 27
Externally publishedYes

Keywords

  • copper
  • heterocycles
  • multicomponent coupling
  • selenium
  • sulfur

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint

Dive into the research topics of 'Versatile synthesis of benzothiophenes and benzoselenophenes by rapid assembly of arylzinc reagents, alkynes, and elemental chalcogens'. Together they form a unique fingerprint.

Cite this