Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system

Rui Lima, Shigeo Wada, Shuji Tanaka, Motohiro Takeda, Ken Ichi Tsubota, Takuji Ishikawa, Takami Yamaguchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper examines the ability to measure the velocity of both physiological saline (PS) and in vitro blood in a rectangular polydimethysiloxane (PDMS) microchannel by means of the confocal micro-PIV system. The PDMS microchannel, was fabricated by conventional soft lithography, had a microchannel near to a perfect rectangular shape (300μm wide, 45μm deep) and was optically transparent, which is suitable to measure both PS and in vitro blood using the confocal system. By using this latter combination, the measurements of trace particles seeded in the flow were performed for both fluids at a constant flow rate (Re=0.021). Generally, all the velocity profiles were found to be markedly blunt in the central region mainly due to the low aspect ratio (h/w=0.15) of the rectangular microchannel. Predictions by a theoretical model for the rectangular microchannel have showed fairly good correspondence with the experimental micro-PIV results for the PS fluid. Conversely, for the in vitro blood with 20% haematocrit, small fluctuations were found on velocity profiles.

Original languageEnglish
Title of host publicationIFMBE Proceedings
EditorsSun I. Kim, Tae Suk Suh
PublisherSpringer Verlag
Pages283-286
Number of pages4
Edition1
ISBN (Print)9783540368397
DOIs
Publication statusPublished - 2007
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 2006 Aug 272006 Sep 1

Publication series

NameIFMBE Proceedings
Number1
Volume14
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Other

Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
CountryKorea, Republic of
CitySeoul
Period06/8/2706/9/1

Keywords

  • Blood flow
  • Confocal micro-PIV
  • Microcirculation
  • PDMS microchannel
  • Red blood cells

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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    Lima, R., Wada, S., Tanaka, S., Takeda, M., Tsubota, K. I., Ishikawa, T., & Yamaguchi, T. (2007). Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system. In S. I. Kim, & T. S. Suh (Eds.), IFMBE Proceedings (1 ed., pp. 283-286). (IFMBE Proceedings; Vol. 14, No. 1). Springer Verlag. https://doi.org/10.1007/978-3-540-36841-0_79