Vascular function

Hiroaki Shimokawa, Kimio Satoh

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)

Abstract

In summary, the interactions among ECs, VSMCs, adventitial tissues, and inflammatory cells regulate vascular functions and diseases. As reviewed in this highlights, recent publications in ATVB have significantly contributed to our understanding on the roles of each vascular cell component for vascular functions in health and disease. These studies have demonstrated the novel mechanistic roles of secreted factors, as well as intracellular signaling for endothelial homeostasis, VSMC proliferation, and inflammatory cell migration. Indeed, we are getting closer to the understanding of fundamental vascular functions and causative cell signaling pathways, all of which should be useful for the development of novel therapeutic strategies in cardiovascular medicine.

Original languageEnglish
Pages (from-to)2359-2362
Number of pages4
JournalArteriosclerosis, thrombosis, and vascular biology
Volume34
Issue number11
DOIs
Publication statusPublished - 2014 Nov 1

Keywords

  • Endothelial cells
  • Muscle, smooth, vascular

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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