Variety and complexity of fluorine-18-labelled fluoro-2-deoxy-D-glucose accumulations in the oral cavity of patients with oral cancers

S. Kito, H. Koga, M. Kodama, M. Habu, S. Kokuryo, N. Yamamoto, M. Oda, T. Nishino, M. Zhang, K. Matsuo, N. Wakasugi-Sato, S. Matsumoto-Takeda, Y. Seta, D. Yoshiga, T. Kaneuji, S. Nogami, I. Yoshioka, Y. Yamashita, T. Tanaka, I. MiyamotoC. Kitamura, K. Tominaga, Y. Morimoto

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8 Citations (Scopus)

Abstract

Objectives: To elucidate the points that require attention when interpreting fluorine-18-labelled fluoro-2-deoxy-D-glucose (18F-FDG)/ positron emission tomography (PET) images by demonstration of 18F-FDG accumulation in various areas of the oral cavity other than primary lesions in patients with oral cancers. Methods: 18F-FDG accumulations with a maximal standardized uptake value of over 2.5 in various areas of the oral cavity other than primary lesions were identified in 82 patients with oral cancers. Results: 18F-FDG/PET-positive areas, excluding primary tumours, included the front intrinsic muscles of the tongue (89.0%), upper and lower marginal parts of the orbicularis oris muscle (64.6%), sublingual glands, palatine tonsil, pharyngeal tonsil, and lingual tonsil. In addition, some areas in the jaws also showed accumulation. Conclusions: In patients with oral cancers, areas of 18F-FDG accumulation in the oral cavity should be precisely identified and appropriately diagnosed, because accumulations can be seen in areas other than the primary tumour.

Original languageEnglish
Article number20130014
JournalDentomaxillofacial Radiology
Volume42
Issue number7
DOIs
Publication statusPublished - 2013 Jul

Keywords

  • Fluorine-18-labelled fluoro-2-deoxy-D-glucose
  • Mimetic muscles
  • Oral cancer
  • Oral cavity
  • Positron emission tomography computerized tomography
  • Tongue

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Radiology Nuclear Medicine and imaging
  • Dentistry(all)

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    Kito, S., Koga, H., Kodama, M., Habu, M., Kokuryo, S., Yamamoto, N., Oda, M., Nishino, T., Zhang, M., Matsuo, K., Wakasugi-Sato, N., Matsumoto-Takeda, S., Seta, Y., Yoshiga, D., Kaneuji, T., Nogami, S., Yoshioka, I., Yamashita, Y., Tanaka, T., ... Morimoto, Y. (2013). Variety and complexity of fluorine-18-labelled fluoro-2-deoxy-D-glucose accumulations in the oral cavity of patients with oral cancers. Dentomaxillofacial Radiology, 42(7), [20130014]. https://doi.org/10.1259/dmfr.20130014