Varieties of right ventricular diastolic function in patients with non-obstructive hyperthrophic cardiomyopathy

Kohtaroh Komaki, Masahito Sakuma, Hidehiko Ishigaki, Hidenari Hozawa, Yoshito Yamamoto, Tohru Takahashi, Norihisa Kumasaka, Yutaka Kagaya, Jun Ikeda, Jun Watanabe, Kunio Shirato

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

We examined whether differences in the location of myocardial hypertrophy influence the right ventricular diastolic function in patients with non-obstructive hypertrophic cardiomyopathy using cineangiography. Biplane right ventriculography was performed in 34 subjects (normal = 14, asymmetric septal hypertrophy = 9, apical hypertrophy = 11) during cardiac catheterization. In patients with asymmetric septal hypertrophy, compared with apical hypertrophy and normal groups, the indices of the right ventricular diastolic function including right ventricular peak filling rate and filling fraction of rapid filling phase were lower and the time to peak filling rate was prolonged. But in patients with apical hypertrophy, these indices were not significantly different compared with normal. There were no differences in right ventricular ejection fraction and cardiac index among the three groups. These data suggest that the location of the myocardial hypertrophy of the left ventricle is a significant factor affecting the right ventricular diastolic filling in non-obstructive hypertrophic cardiomyopathy.

Original languageEnglish
Pages (from-to)49-57
Number of pages9
JournalTohoku Journal of Experimental Medicine
Volume199
Issue number1
DOIs
Publication statusPublished - 2003 Jan 1

Keywords

  • Diastolic function
  • Hypertrohic cardiomyopathy
  • Right ventricle

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Komaki, K., Sakuma, M., Ishigaki, H., Hozawa, H., Yamamoto, Y., Takahashi, T., Kumasaka, N., Kagaya, Y., Ikeda, J., Watanabe, J., & Shirato, K. (2003). Varieties of right ventricular diastolic function in patients with non-obstructive hyperthrophic cardiomyopathy. Tohoku Journal of Experimental Medicine, 199(1), 49-57. https://doi.org/10.1620/tjem.199.49