Variations in 5'-nucleotidase activity in established mesenchymal cell lines from syngeneic A/J mice.

R. Uchino, M. Fukumoto, T. Adachi, O. Midorikawa

Research output: Contribution to journalArticlepeer-review

Abstract

5'-Nucleotidase activity was analyzed in four different mesenchymal cell lines (F, m, e and SP) established from syngeneic A/J mice. The 5'-nucleotidase activity of fibroblasts was lower in transformed cells (F and m) than in nontransformed cells (e). An increase in cell contact during confluence or during high cell density increased 5'-nucleotidase activity, and a decrease in cell contact caused a decrease in 5'-nucleotidase activity in both fibroblastic (F, m and e) and reticulum (SP) cell lines. These results are evidence that 5'-nucleotidase activity in mesenchymal cells is influenced by intercellular contact as well as transformation.

Original languageEnglish
Pages (from-to)119-126
Number of pages8
JournalCell Structure and Function
Volume8
Issue number2
Publication statusPublished - 1983 Jun
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology
  • Physiology
  • Structural Biology

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