Abstract
5'-Nucleotidase activity was analyzed in four different mesenchymal cell lines (F, m, e and SP) established from syngeneic A/J mice. The 5'-nucleotidase activity of fibroblasts was lower in transformed cells (F and m) than in nontransformed cells (e). An increase in cell contact during confluence or during high cell density increased 5'-nucleotidase activity, and a decrease in cell contact caused a decrease in 5'-nucleotidase activity in both fibroblastic (F, m and e) and reticulum (SP) cell lines. These results are evidence that 5'-nucleotidase activity in mesenchymal cells is influenced by intercellular contact as well as transformation.
Original language | English |
---|---|
Pages (from-to) | 119-126 |
Number of pages | 8 |
Journal | Cell Structure and Function |
Volume | 8 |
Issue number | 2 |
Publication status | Published - 1983 Jun |
Externally published | Yes |
ASJC Scopus subject areas
- Cell Biology
- Physiology
- Structural Biology