Variable product specificity of solanesyl pyrophosphate synthetase

Hiroshi Fujii; Hiroshi Sagami; Tanetoshi Koyama; Kyozo Ogura; Shuichi Seto; Tsuneo Baba; Charles M. Allen

doi:10.1016/0006-291X(80)91363-7

Variable product specificity of solanesyl pyrophosphate synthetase

Hiroshi Fujii, Hiroshi Sagami, Tanetoshi Koyama, Kyozo Ogura, Shuichi Seto, Tsuneo Baba, Charles M. Allen

Institute of Multidisciplinary Research for Advanced Materials (IMRAM)

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

The distribution of polyprenyl pyrophosphates synthesized by the action of solanesyl pyrophosphate synthetase from Micrococcus luteus is dramatically changed depending on the Mg⁺⁺ concentration. When the metal ion concentration is higher than 5 mM, octaprenyl and solanesyl (nonaprenyl) pyrophosphate are synthesized predominantly. On the other hand, when the metal ion level is lower than 0.5 mM, a variety of polyprenyl pyrophosphates ranging in carbon chain length from C₁₅ to C₄₀ are formed. Heptaprenyl pyrophosphate is the longest of the products formed at 0.1 mM of Mg⁺⁺.

Original language	English
Pages (from-to)	1648-1653
Number of pages	6
Journal	Topics in Catalysis
Volume	96
Issue number	4
DOIs	https://doi.org/10.1016/0006-291X(80)91363-7
Publication status	Published - 1980

Keywords

HPLC
PP
high pressure liquid chromatography
pyrophosphate

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Biophysics
Molecular Biology

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10.1016/0006-291X(80)91363-7

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@article{93487f80e9174a05badcac75211572a2,

title = "Variable product specificity of solanesyl pyrophosphate synthetase",

abstract = "The distribution of polyprenyl pyrophosphates synthesized by the action of solanesyl pyrophosphate synthetase from Micrococcus luteus is dramatically changed depending on the Mg++ concentration. When the metal ion concentration is higher than 5 mM, octaprenyl and solanesyl (nonaprenyl) pyrophosphate are synthesized predominantly. On the other hand, when the metal ion level is lower than 0.5 mM, a variety of polyprenyl pyrophosphates ranging in carbon chain length from C15 to C40 are formed. Heptaprenyl pyrophosphate is the longest of the products formed at 0.1 mM of Mg++.",

keywords = "HPLC, PP, high pressure liquid chromatography, pyrophosphate",

author = "Hiroshi Fujii and Hiroshi Sagami and Tanetoshi Koyama and Kyozo Ogura and Shuichi Seto and Tsuneo Baba and Allen, {Charles M.}",

note = "Funding Information: This work was supported by a Grant-in-Aid for Encouragement of Young Scientist (474242) from the Ministry of Education, Science and Culture of Japan.",

year = "1980",

doi = "10.1016/0006-291X(80)91363-7",

language = "English",

volume = "96",

pages = "1648--1653",

journal = "Topics in Catalysis",

number = "4",

}

TY - JOUR

T1 - Variable product specificity of solanesyl pyrophosphate synthetase

AU - Fujii, Hiroshi

AU - Sagami, Hiroshi

AU - Koyama, Tanetoshi

AU - Ogura, Kyozo

AU - Seto, Shuichi

AU - Baba, Tsuneo

AU - Allen, Charles M.

N1 - Funding Information: This work was supported by a Grant-in-Aid for Encouragement of Young Scientist (474242) from the Ministry of Education, Science and Culture of Japan.

PY - 1980

Y1 - 1980

N2 - The distribution of polyprenyl pyrophosphates synthesized by the action of solanesyl pyrophosphate synthetase from Micrococcus luteus is dramatically changed depending on the Mg++ concentration. When the metal ion concentration is higher than 5 mM, octaprenyl and solanesyl (nonaprenyl) pyrophosphate are synthesized predominantly. On the other hand, when the metal ion level is lower than 0.5 mM, a variety of polyprenyl pyrophosphates ranging in carbon chain length from C15 to C40 are formed. Heptaprenyl pyrophosphate is the longest of the products formed at 0.1 mM of Mg++.

AB - The distribution of polyprenyl pyrophosphates synthesized by the action of solanesyl pyrophosphate synthetase from Micrococcus luteus is dramatically changed depending on the Mg++ concentration. When the metal ion concentration is higher than 5 mM, octaprenyl and solanesyl (nonaprenyl) pyrophosphate are synthesized predominantly. On the other hand, when the metal ion level is lower than 0.5 mM, a variety of polyprenyl pyrophosphates ranging in carbon chain length from C15 to C40 are formed. Heptaprenyl pyrophosphate is the longest of the products formed at 0.1 mM of Mg++.

KW - HPLC

KW - PP

KW - high pressure liquid chromatography

KW - pyrophosphate

UR - http://www.scopus.com/inward/record.url?scp=0019336842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019336842&partnerID=8YFLogxK

U2 - 10.1016/0006-291X(80)91363-7

DO - 10.1016/0006-291X(80)91363-7

M3 - Article

C2 - 7447947

AN - SCOPUS:0019336842

VL - 96

SP - 1648

EP - 1653

JO - Topics in Catalysis

JF - Topics in Catalysis

IS - 4

ER -

Variable product specificity of solanesyl pyrophosphate synthetase

Abstract

Keywords

ASJC Scopus subject areas

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