Vallartanone B: Synthesis and related studies

Hirokazu Arimoto, Rieko Yokoyama, Kazuhiko Nakamura, Yasuaki Okumura, Daisuke Uemura

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


The synthesis of vallartanone B, a γ-pyrone-containing polypoprionate from the marine mollusc Siphonaria maura, is described. A γ-pyrone moiety, which was constructed by PPh3-CCl4 cyclization of a β-triketone, and a C1-C6 segment were joined by a Sn(OTf)2 aldol reaction and converted to vallartanone B. This synthesis allows for revision of the stereochemistry at C8. A conformational analysis was performed using PM3 to examine the proposed interpretation of its CD spectrum.

Original languageEnglish
Pages (from-to)13901-13908
Number of pages8
Issue number44
Publication statusPublished - 1996 Oct 28
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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