TY - JOUR
T1 - Vacuolar digestion of entire damaged chloroplasts in Arabidopsis thaliana is accomplished by chlorophagy
AU - Izumi, Masanori
AU - Nakamura, Sakuya
N1 - Publisher Copyright:
© 2017 Taylor & Francis.
PY - 2017/7/3
Y1 - 2017/7/3
N2 - In yeast and mammals, selective vacuolar delivery and degradation of whole mitochondria, or mitophagy, represents an important quality control system and is achieved by a cargo recognition mechanism enabling selective elimination of dysfunctional mitochondria. As photosynthetic organelles that need light for energy production, plant chloroplasts accumulate sunlight-induced damage. Plants have evolved multiple mechanisms to avoid, relieve, or repair chloroplast photodamage. Our recent study showed that vacuolar degradation of entire chloroplasts, termed chlorophagy, is induced to degrade chloroplasts that are collapsed due to photodamage. Our results underscore the involvement of autophagy in the quality control of endosymbiotic, energy-converting organelles in eukaryotes.
AB - In yeast and mammals, selective vacuolar delivery and degradation of whole mitochondria, or mitophagy, represents an important quality control system and is achieved by a cargo recognition mechanism enabling selective elimination of dysfunctional mitochondria. As photosynthetic organelles that need light for energy production, plant chloroplasts accumulate sunlight-induced damage. Plants have evolved multiple mechanisms to avoid, relieve, or repair chloroplast photodamage. Our recent study showed that vacuolar degradation of entire chloroplasts, termed chlorophagy, is induced to degrade chloroplasts that are collapsed due to photodamage. Our results underscore the involvement of autophagy in the quality control of endosymbiotic, energy-converting organelles in eukaryotes.
KW - Arabidopsis thaliana
KW - autophagy
KW - chlorophagy
KW - chloroplasts
KW - photodamage
KW - plants
KW - reactive oxygen species
KW - ultraviolet-B
UR - http://www.scopus.com/inward/record.url?scp=85019690477&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019690477&partnerID=8YFLogxK
U2 - 10.1080/15548627.2017.1310360
DO - 10.1080/15548627.2017.1310360
M3 - Comment/debate
C2 - 28548870
AN - SCOPUS:85019690477
VL - 13
SP - 1239
EP - 1240
JO - Autophagy
JF - Autophagy
SN - 1554-8627
IS - 7
ER -