Utility of micro-filter membrane in THz spectrum of molecules in solution

H. Yoneyama, M. Yamashita, S. Kasai, H. Ito, T. Ouchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)


We report the experimental results of physiologically active substances including hormones utilizing Terahertz (THz) spectrum technology. Various analytical techniques have been employed for the determination of physiologically active substances. Most of methods used oxidation reagent and sodium sulfite stabilization reagent or fluorescent reagent. These methods had a good selectivity, but the stability of samples was not satisfactory. The direct detection method has not been advanced yet. In this study, the THz characteristics of physiologically active substances were measured directly. We found all of samples have their vibrational features like signature peaks either in pellet and/or sample solution. A membrane device was used to hold the sample solution in this study. This device allows samples to be prepared in solutions and measured easily with THz measurement system after dried. Results suggest that this membrane device is sensitive for detecting the physiologically active substances in THz ranges. THz spectrum technology has the potential to be a useful tool in clinical applications. This approach promotes the understanding of the relationships between biomolecules with THz radiation.

Original languageEnglish
Title of host publicationBiomedical Optical Spectroscopy
Publication statusPublished - 2008
Externally publishedYes
EventBiomedical Optical Spectroscopy - San Jose, CA, United States
Duration: 2008 Jan 192008 Jan 23

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherBiomedical Optical Spectroscopy
Country/TerritoryUnited States
CitySan Jose, CA


  • Biomolecules
  • FT-IR
  • Membrane device
  • Physiologically active substances
  • TDS measurement system

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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