Using polyethylene glycol 3350 plus electrolytes in constipated hemodialysis patients: A case series

Hiroyuki Endo, Noriyuki Obara, Takashi Watanabe, Satoru Sanada, Tomoyuki Koike, Atsushi Masamune

Research output: Contribution to journalArticlepeer-review

Abstract

Appropriate management of constipation in hemodialysis patients has not been established, although constipation is the most frequent gastrointestinal complication in dialysis patients. We herein report the efficacy and safety of polyethylene glycol in constipated hemodialysis patients assessed prospectively. Seven patients using stimulant laxatives participated in this study. Polyethylene glycol was administered to reduce stimulant laxatives during the six-week intervention period. The amount of stimulant laxatives decreased and spontaneous bowel movements with ideal stool consistency increased significantly after the intervention. No serious adverse effects were observed throughout this study. In conclusion, polyethylene glycol can be a useful tool for managing constipated hemodialysis patients.

Original languageEnglish
Pages (from-to)379-384
Number of pages6
JournalInternal Medicine
Volume60
Issue number3
DOIs
Publication statusPublished - 2021 Feb 1

Keywords

  • Constipation
  • Hemodialysis
  • Medication
  • Polyethylene glycol
  • Stimulant laxative

ASJC Scopus subject areas

  • Internal Medicine

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