Usefulness of z-score mapping for quantification of extent of hypoattenuation regions of hyperacute stroke in unenhanced computed tomography: Analysis of radiologist's performance

Noriyuki Takahashi, Du Yih Tsai, Yongbum Lee, Toshibumi Kinoshita, Kiyoshi Ishii, Hajime Tamura, Shoki Takahashi

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the usefulness of z-score mapping method on neuroradiologists' performance in quantification of the extent of hypoattenuation regions of hyperacute stroke on unenhanced computed tomographic (CT) images by using the Alberta Stroke Programme Early CT Score system. Methods: Twenty-one patients with infarction (<3 hours) were retrospectively selected. Five neuroradiologists interpreted CT images first without and then with z-score maps by using the Alberta Stroke Programme Early CT Score system. Their performances in the quantification of the extent of hypoattenuation were compared. Results: Average accuracies for the quantification without and with the z-score maps were 82.6% and 86.6%, respectively (P < 0.0001). The average area under the receiver operating characteristic curve for detection of focal hypoattenuation significantly increased from 0.883 to 0.925 (P = 0.01) by use of z-score maps. Conclusions: The use of z-score mapping method has the potential to help neuroradiologists quantify the extent of hypoattenuation regions of hyperacute stroke on unenhanced CT images.

Original languageEnglish
Pages (from-to)751-756
Number of pages6
JournalJournal of Computer Assisted Tomography
Volume34
Issue number5
DOIs
Publication statusPublished - 2010 Sep
Externally publishedYes

Keywords

  • Hyperacute stroke
  • Hypoattenuation
  • Observer study
  • Receiver operating characteristic analysis
  • Z score

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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