Usefulness of Diffusion-Weighted Magnetic Resonance Imaging Using Apparent Diffusion Coefficient Values for Diagnosis of Infantile Hemangioma

Mioko Saito, Masahiro Kitami, Kei Takase

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The objective of this study was to determine whether apparent diffusion coefficient (ADC) values obtained from diffusion-weighted imaging allow differentiation between infantile hemangiomas (IHs) and malignant soft tissue tumors. Methods: A retrospective review was performed on magnetic resonance images of pediatric patients with IHs and malignant soft tissue tumors from January 2014 to December 2016, which comprised 7 patients with 8 IHs and 6 patients with 6 malignant soft tissue tumors. We calculated and compared the ADC values of each lesion. Receiver operating characteristic curve analysis was performed to determine a cutoff value for the ADC. Results: There was a statistically significant difference between the ADC values of IHs and those of malignant soft tissue tumors (1.32 [1.27-1.72] × 10-3 mm2/s vs 0.67 [0.57-0.79] × 10-3 mm2/s; P < 0.001), with no overlap between the 2 groups. Conclusions: The ADC values obtained from diffusion-weighted imaging were useful in differentiating IHs from malignant soft tissue tumors in pediatric patients.

Original languageEnglish
Pages (from-to)563-567
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume43
Issue number4
DOIs
Publication statusPublished - 2019 Jul 1

Keywords

  • apparent diffusion coefficient values
  • child
  • diffusion magnetic resonance imaging
  • infantile hemangioma
  • sarcoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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