Use Liposome as a Designable Platform for Molecular Recognition ~ from “Statistical Separation” to “Recognitive Separation”

Hiroshi Umakoshi, Keishi Suga

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A liposome membrane system attracts much interest for its use as a “designable” interface for the recognition of various biomolecules because it can provide a hydrophobic nano-environment in aqueous solution and can also induce a dynamic nature in response to the variation of its environment. The methods to characterize the membrane properties of liposome have been reviewed, focusing on the micro-phase separation of different lipids on the membrane and, also, nano-domain formation there. A possible design of the liposome membrane for the recognition of biomacromolecules was discussed based on the characterized properties, by employing the RNA molecule as a case study. Finally, a possible extension of the above-described strategy toward “recognitive separation” is discussed as a future possibility.

Original languageEnglish
Pages (from-to)1-13
Number of pages13
JournalSolvent Extraction Research and Development
Volume20
DOIs
Publication statusPublished - 2013 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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