Urea Sensor Based on an Ion-Sensitive Field Effect Transistor. III.1) Effects of Enzyme Load and Ionic Strength on the Potentiometric Response

Jun Ichia Anzai, Sachiko Tezuka, Tetsuo Osa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The effects of ionic strength of the sample solution and enzyme load on the potentiometric response of a urea sensor based on an ion-sensitive field effect transistor (ISFET) were examined. The output voltage of the sensor for urea solutions shifted slightly when NaCl was added to the solutions. The enzyme load on the ISFET gate affected the potentiometric response significantly. The sensor showed a higher response when the ISFET gate was coated with an enzyme membrane with a higher content of urease.

Original languageEnglish
Pages (from-to)4373-4376
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume34
Issue number10
DOIs
Publication statusPublished - 1986 Jan 1

Keywords

  • enzyme sensor
  • ion-sensitive field effect transistor
  • urea sensor
  • urease

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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