Urea Sensor Based on an Ion-Sensitive Field Effect Transistor. III.1) Effects of Enzyme Load and Ionic Strength on the Potentiometric Response

Jun Ichia Anzai; Sachiko Tezuka; Tetsuo Osa

doi:10.1248/cpb.34.4373

Urea Sensor Based on an Ion-Sensitive Field Effect Transistor. III.¹⁾ Effects of Enzyme Load and Ionic Strength on the Potentiometric Response

Jun Ichia Anzai, Sachiko Tezuka, Tetsuo Osa

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The effects of ionic strength of the sample solution and enzyme load on the potentiometric response of a urea sensor based on an ion-sensitive field effect transistor (ISFET) were examined. The output voltage of the sensor for urea solutions shifted slightly when NaCl was added to the solutions. The enzyme load on the ISFET gate affected the potentiometric response significantly. The sensor showed a higher response when the ISFET gate was coated with an enzyme membrane with a higher content of urease.

Original language	English
Pages (from-to)	4373-4376
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	34
Issue number	10
DOIs	https://doi.org/10.1248/cpb.34.4373
Publication status	Published - 1986
Externally published	Yes

Keywords

enzyme sensor
ion-sensitive field effect transistor
urea sensor
urease

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

Access to Document

10.1248/cpb.34.4373

Cite this

@article{bc86f500b6e34d2480f96a06ee6508a2,

title = "Urea Sensor Based on an Ion-Sensitive Field Effect Transistor. III.1) Effects of Enzyme Load and Ionic Strength on the Potentiometric Response",

abstract = "The effects of ionic strength of the sample solution and enzyme load on the potentiometric response of a urea sensor based on an ion-sensitive field effect transistor (ISFET) were examined. The output voltage of the sensor for urea solutions shifted slightly when NaCl was added to the solutions. The enzyme load on the ISFET gate affected the potentiometric response significantly. The sensor showed a higher response when the ISFET gate was coated with an enzyme membrane with a higher content of urease.",

keywords = "enzyme sensor, ion-sensitive field effect transistor, urea sensor, urease",

author = "Anzai, {Jun Ichia} and Sachiko Tezuka and Tetsuo Osa",

year = "1986",

doi = "10.1248/cpb.34.4373",

language = "English",

volume = "34",

pages = "4373--4376",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "10",

}

TY - JOUR

T1 - Urea Sensor Based on an Ion-Sensitive Field Effect Transistor. III.1) Effects of Enzyme Load and Ionic Strength on the Potentiometric Response

AU - Anzai, Jun Ichia

AU - Tezuka, Sachiko

AU - Osa, Tetsuo

PY - 1986

Y1 - 1986

N2 - The effects of ionic strength of the sample solution and enzyme load on the potentiometric response of a urea sensor based on an ion-sensitive field effect transistor (ISFET) were examined. The output voltage of the sensor for urea solutions shifted slightly when NaCl was added to the solutions. The enzyme load on the ISFET gate affected the potentiometric response significantly. The sensor showed a higher response when the ISFET gate was coated with an enzyme membrane with a higher content of urease.

AB - The effects of ionic strength of the sample solution and enzyme load on the potentiometric response of a urea sensor based on an ion-sensitive field effect transistor (ISFET) were examined. The output voltage of the sensor for urea solutions shifted slightly when NaCl was added to the solutions. The enzyme load on the ISFET gate affected the potentiometric response significantly. The sensor showed a higher response when the ISFET gate was coated with an enzyme membrane with a higher content of urease.

KW - enzyme sensor

KW - ion-sensitive field effect transistor

KW - urea sensor

KW - urease

UR - http://www.scopus.com/inward/record.url?scp=85004271300&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85004271300&partnerID=8YFLogxK

U2 - 10.1248/cpb.34.4373

DO - 10.1248/cpb.34.4373

M3 - Article

AN - SCOPUS:85004271300

SN - 0009-2363

VL - 34

SP - 4373

EP - 4376

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 10

ER -