Unraveling the roles of sphingolipids in plant innate immunity

Yoshihiro Takahashi, Thomas Berberich, Hiroyuki Kanzaki, Hideo Matsumura, Hiromasa Saitoh, Tomonobu Kusano, Ryohei Terauchi

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    It has long been known that fungal pathogens like Fusarium and Alternaria spp. produce toxins (mycotoxin) to kill plant cells. These mycotoxins have been shown to perturb the plant sphingolipid biosynthesis pathway, resulting in the necrotic cell death of plant cells. A recent study by Shi et al.1 revealed that an increase in the amount of cellular sphingoid bases triggers plant programmed cell death (PCD) through accumulation of reactive oxygen species (ROS). These findings point to the importance of sphingolipids in the regulation of plant cell in disease development as well as in defense responses. In the latest report,2 we showed that serine palmitoyltransferase (SPT), the key enzyme of sphingolipid biosynthesis, regulates not only plant cell death but also defense response against a non-host pathogen, soliciting further studies to elucidate the roles of sphingolipids in plant innate immunity.

    Original languageEnglish
    Pages (from-to)536-538
    Number of pages3
    JournalPlant Signaling and Behavior
    Volume4
    Issue number6
    DOIs
    Publication statusPublished - 2009 Jun

    Keywords

    • Cell death
    • Defense response
    • Plant
    • Serine palmitoyltransferase
    • Sphingolipid

    ASJC Scopus subject areas

    • Plant Science

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  • Cite this

    Takahashi, Y., Berberich, T., Kanzaki, H., Matsumura, H., Saitoh, H., Kusano, T., & Terauchi, R. (2009). Unraveling the roles of sphingolipids in plant innate immunity. Plant Signaling and Behavior, 4(6), 536-538. https://doi.org/10.4161/psb.4.6.8583