Unique molecular properties of superoxide dismutase from teleost fish skin

Toshiki Nakano; Minoru Sato; Masaaki Takeuchi

doi:10.1016/0014-5793(95)00084-M

Unique molecular properties of superoxide dismutase from teleost fish skin

Toshiki Nakano, Minoru Sato, Masaaki Takeuchi

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

A unique Cu,ZnSOD was found and isolated from plaice Paralichthys olivaceus skin. Surprisingly, the properties of purified fish skin SOD were very different from those of SOD from other sources reported so far. The purified SOD was composed of four same subunits of 16 kDa and the molecular weight of the native SOD was found to be around 65 kDa. The dominant amino acids of the SOD were Ser, Thr, Pro and Glu. Above 70°C, thermostability of the SOD was much lower than that of bovine erythrocyte Cu,ZnSOD.

Original language	English
Pages (from-to)	197-201
Number of pages	5
Journal	FEBS Letters
Volume	360
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(95)00084-M
Publication status	Published - 1995 Feb 27

Keywords

Fish skin
Molecular properties
Paralichthys olivaceus
Superoxide dismutase
Teleost
Thermostability

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(95)00084-M

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title = "Unique molecular properties of superoxide dismutase from teleost fish skin",

abstract = "A unique Cu,ZnSOD was found and isolated from plaice Paralichthys olivaceus skin. Surprisingly, the properties of purified fish skin SOD were very different from those of SOD from other sources reported so far. The purified SOD was composed of four same subunits of 16 kDa and the molecular weight of the native SOD was found to be around 65 kDa. The dominant amino acids of the SOD were Ser, Thr, Pro and Glu. Above 70°C, thermostability of the SOD was much lower than that of bovine erythrocyte Cu,ZnSOD.",

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T1 - Unique molecular properties of superoxide dismutase from teleost fish skin

AU - Nakano, Toshiki

AU - Sato, Minoru

AU - Takeuchi, Masaaki

PY - 1995/2/27

Y1 - 1995/2/27

N2 - A unique Cu,ZnSOD was found and isolated from plaice Paralichthys olivaceus skin. Surprisingly, the properties of purified fish skin SOD were very different from those of SOD from other sources reported so far. The purified SOD was composed of four same subunits of 16 kDa and the molecular weight of the native SOD was found to be around 65 kDa. The dominant amino acids of the SOD were Ser, Thr, Pro and Glu. Above 70°C, thermostability of the SOD was much lower than that of bovine erythrocyte Cu,ZnSOD.

AB - A unique Cu,ZnSOD was found and isolated from plaice Paralichthys olivaceus skin. Surprisingly, the properties of purified fish skin SOD were very different from those of SOD from other sources reported so far. The purified SOD was composed of four same subunits of 16 kDa and the molecular weight of the native SOD was found to be around 65 kDa. The dominant amino acids of the SOD were Ser, Thr, Pro and Glu. Above 70°C, thermostability of the SOD was much lower than that of bovine erythrocyte Cu,ZnSOD.

KW - Fish skin

KW - Molecular properties

KW - Paralichthys olivaceus

KW - Superoxide dismutase

KW - Teleost

KW - Thermostability

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Unique molecular properties of superoxide dismutase from teleost fish skin

Abstract

Keywords

ASJC Scopus subject areas

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