Unique molecular properties of superoxide dismutase from teleost fish skin

Toshiki Nakano, Minoru Sato, Masaaki Takeuchi

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

A unique Cu,ZnSOD was found and isolated from plaice Paralichthys olivaceus skin. Surprisingly, the properties of purified fish skin SOD were very different from those of SOD from other sources reported so far. The purified SOD was composed of four same subunits of 16 kDa and the molecular weight of the native SOD was found to be around 65 kDa. The dominant amino acids of the SOD were Ser, Thr, Pro and Glu. Above 70°C, thermostability of the SOD was much lower than that of bovine erythrocyte Cu,ZnSOD.

Original languageEnglish
Pages (from-to)197-201
Number of pages5
JournalFEBS Letters
Volume360
Issue number2
DOIs
Publication statusPublished - 1995 Feb 27

Keywords

  • Fish skin
  • Molecular properties
  • Paralichthys olivaceus
  • Superoxide dismutase
  • Teleost
  • Thermostability

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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