Unilateral chronic pulsatile headache as the single manifestation of anti-MOG antibody-associated unilateral cerebral cortical encephalitis

Juichi Fujimori, Ryo Ogawa, Takaki Murata, Kazutaka Jin, Yukako Yazawa, Ichiro Nakashima

Research output: Contribution to journalArticle

Abstract

Unilateral cerebral cortical encephalitis (UCCE) with myelin oligodendrocyte glycoprotein (MOG)-antibody comprises a new spectrum of disease entities generally presenting seizures. Here, we report a case of a young adult with anti-MOG antibody-associated UCCE who only presented persistent left pulsatile headache. Neurological examination revealed no deficits. Brain MRI showed a fluid-attenuated inversion recovery hyperintense lesion along the swollen left cerebral cortex. The patient was positive for anti-MOG antibodies. We diagnosed him with anti-MOG antibody-associated UCCE. Immediately after the administration of high-dose IV methylprednisolone, the headache diminished. Anti-MOG antibody-associated UCCE is a new differential diagnosis in patients with unilateral chronic pulsatile headache.

Original languageEnglish
Article number577322
JournalJournal of Neuroimmunology
Volume346
DOIs
Publication statusPublished - 2020 Sep 15

Keywords

  • Encephalitis
  • MRA
  • Migraine
  • Myelin oligodendrocyte glycoprotein
  • Vasodilatation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Neurology
  • Clinical Neurology

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