Under-estimation of baroreflex sensitivity through a closed loop model due to non-gaussian property of blood pressure distribution

Research output: Contribution to journalConference articlepeer-review

Abstract

Non-invasive estimation of baroreflex sensitivity (BRS) is one of major targets of cardiovascular dynamics analyses including the sequence method and the closed loop modeling. However, the closed loop model is known to under-estimate BRS in comparison with that by the sequence method and the vasoactive agent injection. In this paper, BRSs for sleep-waking states are estimated by applying the sequence method to the multivariate time series measured from the actual cardiovascular system. The same estimation is performed to the time series generated by the multivariate autoregressive (MAR) model driven by the innovation process. The result shows the MAR model-based method under-estimates BRS in comparison with that for the actual data. It is suggested that the under-estimation is attributed to non-Gaussian property of blood pressure distribution.

Original languageEnglish
Pages (from-to)1613-1614
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
Publication statusPublished - 2002 Dec 1
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: 2002 Oct 232002 Oct 26

Keywords

  • Baroreflex sensitivity
  • Closed loop model
  • Sequence method

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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