Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell

T. Iwata; Takashi Katagiri; Yuji Matsuura

doi:10.1117/12.2249662

Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell

T. Iwata, Takashi Katagiri, Yuji Matsuura

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

For breath analysis on ultraviolet absorption spectroscopy, an analysis system using a hollow optical fiber as gas cell is developed. The hollow optical fiber functions as a long path and extremely small volume gas cell. Firstly, the measurement sensitivity of the system is evaluated by using NO gas as a gas sample. The result shows that NO gas with 50 ppb concentration is measured by using a system with a laser-driven, high intensity light source and a 3-meter long, aluminum-coated hollow optical fiber. Then an absorption spectrum of breath sample is measured in the wavelength region of around 200-300 nm and from the spectrum, it is found that the main absorbing components in breath were H₂O, isoprene, and O₃ converted from O₂ by radiation of ultraviolet light. Then the concentration of isoprene in breath is estimated by using multiple linear regression analysis.

Original language	English
Title of host publication	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
Editors	Israel Gannot, Israel Gannot
Publisher	SPIE
ISBN (Electronic)	9781510605572
DOIs	https://doi.org/10.1117/12.2249662
Publication status	Published - 2017 Jan 1
Event	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII - San Francisco, United States Duration: 2017 Jan 28 → 2017 Jan 29

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10058
ISSN (Print)	1605-7422

Other

Other	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
Country	United States
City	San Francisco
Period	17/1/28 → 17/1/29

Keywords

Breath analysis
Hollow-optical fiber
Isoprene
Ultraviolet spectroscopy

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

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Iwata, T., Katagiri, T., & Matsuura, Y. (2017). Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell. In I. Gannot, & I. Gannot (Eds.), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII [1005806] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10058). SPIE. https://doi.org/10.1117/12.2249662

Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell. / Iwata, T.; Katagiri, Takashi; Matsuura, Yuji.

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII. ed. / Israel Gannot; Israel Gannot. SPIE, 2017. 1005806 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10058).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Iwata, T, Katagiri, T & Matsuura, Y 2017, Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell. in I Gannot & I Gannot (eds), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII., 1005806, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10058, SPIE, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII, San Francisco, United States, 17/1/28. https://doi.org/10.1117/12.2249662

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abstract = "For breath analysis on ultraviolet absorption spectroscopy, an analysis system using a hollow optical fiber as gas cell is developed. The hollow optical fiber functions as a long path and extremely small volume gas cell. Firstly, the measurement sensitivity of the system is evaluated by using NO gas as a gas sample. The result shows that NO gas with 50 ppb concentration is measured by using a system with a laser-driven, high intensity light source and a 3-meter long, aluminum-coated hollow optical fiber. Then an absorption spectrum of breath sample is measured in the wavelength region of around 200-300 nm and from the spectrum, it is found that the main absorbing components in breath were H2O, isoprene, and O3 converted from O2 by radiation of ultraviolet light. Then the concentration of isoprene in breath is estimated by using multiple linear regression analysis.",

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