TY - GEN
T1 - Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell
AU - Iwata, T.
AU - Katagiri, Takashi
AU - Matsuura, Yuji
PY - 2017/1/1
Y1 - 2017/1/1
N2 - For breath analysis on ultraviolet absorption spectroscopy, an analysis system using a hollow optical fiber as gas cell is developed. The hollow optical fiber functions as a long path and extremely small volume gas cell. Firstly, the measurement sensitivity of the system is evaluated by using NO gas as a gas sample. The result shows that NO gas with 50 ppb concentration is measured by using a system with a laser-driven, high intensity light source and a 3-meter long, aluminum-coated hollow optical fiber. Then an absorption spectrum of breath sample is measured in the wavelength region of around 200-300 nm and from the spectrum, it is found that the main absorbing components in breath were H2O, isoprene, and O3 converted from O2 by radiation of ultraviolet light. Then the concentration of isoprene in breath is estimated by using multiple linear regression analysis.
AB - For breath analysis on ultraviolet absorption spectroscopy, an analysis system using a hollow optical fiber as gas cell is developed. The hollow optical fiber functions as a long path and extremely small volume gas cell. Firstly, the measurement sensitivity of the system is evaluated by using NO gas as a gas sample. The result shows that NO gas with 50 ppb concentration is measured by using a system with a laser-driven, high intensity light source and a 3-meter long, aluminum-coated hollow optical fiber. Then an absorption spectrum of breath sample is measured in the wavelength region of around 200-300 nm and from the spectrum, it is found that the main absorbing components in breath were H2O, isoprene, and O3 converted from O2 by radiation of ultraviolet light. Then the concentration of isoprene in breath is estimated by using multiple linear regression analysis.
KW - Breath analysis
KW - Hollow-optical fiber
KW - Isoprene
KW - Ultraviolet spectroscopy
UR - http://www.scopus.com/inward/record.url?scp=85018862351&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018862351&partnerID=8YFLogxK
U2 - 10.1117/12.2249662
DO - 10.1117/12.2249662
M3 - Conference contribution
AN - SCOPUS:85018862351
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
A2 - Gannot, Israel
A2 - Gannot, Israel
PB - SPIE
T2 - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
Y2 - 28 January 2017 through 29 January 2017
ER -