Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell

T. Iwata, Takashi Katagiri, Yuji Matsuura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

For breath analysis on ultraviolet absorption spectroscopy, an analysis system using a hollow optical fiber as gas cell is developed. The hollow optical fiber functions as a long path and extremely small volume gas cell. Firstly, the measurement sensitivity of the system is evaluated by using NO gas as a gas sample. The result shows that NO gas with 50 ppb concentration is measured by using a system with a laser-driven, high intensity light source and a 3-meter long, aluminum-coated hollow optical fiber. Then an absorption spectrum of breath sample is measured in the wavelength region of around 200-300 nm and from the spectrum, it is found that the main absorbing components in breath were H2O, isoprene, and O3 converted from O2 by radiation of ultraviolet light. Then the concentration of isoprene in breath is estimated by using multiple linear regression analysis.

Original languageEnglish
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
EditorsIsrael Gannot, Israel Gannot
PublisherSPIE
ISBN (Electronic)9781510605572
DOIs
Publication statusPublished - 2017 Jan 1
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII - San Francisco, United States
Duration: 2017 Jan 282017 Jan 29

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10058
ISSN (Print)1605-7422

Other

OtherOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
CountryUnited States
CitySan Francisco
Period17/1/2817/1/29

Keywords

  • Breath analysis
  • Hollow-optical fiber
  • Isoprene
  • Ultraviolet spectroscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Iwata, T., Katagiri, T., & Matsuura, Y. (2017). Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell. In I. Gannot, & I. Gannot (Eds.), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII [1005806] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10058). SPIE. https://doi.org/10.1117/12.2249662