TY - GEN
T1 - Ultrasonic and photoacoustic imaging of knee joints in normal and osteoarthritis rats
AU - Izumi, Takuya
AU - Sato, Mika
AU - Yabe, Yutaka
AU - Hagiwara, Yoshihiro
AU - Saijo, Yoshifumi
PY - 2013/10/31
Y1 - 2013/10/31
N2 - Osteoarthritis (OA) is a common joint disorder and estimated to cause symptoms in 20-40% of the elderly population. 532 nm laser is much absorbed in developed vascular network in the spongy bone which is one of the main characteristics of OA. In this study, a photoacoustic (PA) imaging system with 532 nm laser and 50 MHz US (ultrasound) transducer was developed. Normal and OA knee joints were observed by US and PA imaging. PA signal from the spongy bone was strong where US reflection was very weak. PA signal from the spongy bone was significantly strong in OA compared with that in normal knee while US showed similar low intensity echo in normal and OA. Detailed structure and information on vascular density of spongy bone in rat knee joint were successfully obtained with US / PA combined imaging. US / PA imaging should be useful for early diagnosis of OA.
AB - Osteoarthritis (OA) is a common joint disorder and estimated to cause symptoms in 20-40% of the elderly population. 532 nm laser is much absorbed in developed vascular network in the spongy bone which is one of the main characteristics of OA. In this study, a photoacoustic (PA) imaging system with 532 nm laser and 50 MHz US (ultrasound) transducer was developed. Normal and OA knee joints were observed by US and PA imaging. PA signal from the spongy bone was strong where US reflection was very weak. PA signal from the spongy bone was significantly strong in OA compared with that in normal knee while US showed similar low intensity echo in normal and OA. Detailed structure and information on vascular density of spongy bone in rat knee joint were successfully obtained with US / PA combined imaging. US / PA imaging should be useful for early diagnosis of OA.
UR - http://www.scopus.com/inward/record.url?scp=84886493195&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886493195&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2013.6609701
DO - 10.1109/EMBC.2013.6609701
M3 - Conference contribution
C2 - 24109888
AN - SCOPUS:84886493195
SN - 9781457702167
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 1116
EP - 1119
BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
T2 - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Y2 - 3 July 2013 through 7 July 2013
ER -