TY - JOUR
T1 - Ubiquitin-proteasome-dependent regulation of bidirectionalcommunication between plastids and the nucleus
AU - Hirosawa, Yoshihiro
AU - Ito-Inaba, Yasuko
AU - Inaba, Takehito
N1 - Funding Information:
This work was supported in part by Grants-in-Aid for Scientific Research (15K07843), Grants-in-Aid for Young Scientists (B, No. 26850065), the Program to Disseminate Tenure Tracking System from the Japanese Ministry of Education, Culture, Sports, Science, and Technology.
Publisher Copyright:
© 2017 Hirosawa, Ito-Inaba and Inaba.
PY - 2017/3/15
Y1 - 2017/3/15
N2 - Plastids are DNA-containing organelles and can have unique differentiation states depending on age, tissue, and environment. Plastid biogenesis is optimized by bidirectional communication between plastids and the nucleus. Import of nuclear-encoded proteins into plastids serves as anterograde signals and vice versa, plastids themselves send retrograde signals to the nucleus, thereby controlling de novo synthesis of nuclear-encoded plastid proteins. Recently, it has become increasingly evident that the ubiquitin-proteasome system regulates both the import of anterograde plastid proteins and retrograde signaling from plastids to the nucleus. Targets of ubiquitin-proteasome regulation include unimported chloroplast precursor proteins in the cytosol, protein translocation machinery at the chloroplast surface, and transcription factors in the nucleus. This review will focus on the mechanism through which the ubiquitin-proteasome system optimizes plastid biogenesis and plant development through the regulation of nuclear-plastid interactions.
AB - Plastids are DNA-containing organelles and can have unique differentiation states depending on age, tissue, and environment. Plastid biogenesis is optimized by bidirectional communication between plastids and the nucleus. Import of nuclear-encoded proteins into plastids serves as anterograde signals and vice versa, plastids themselves send retrograde signals to the nucleus, thereby controlling de novo synthesis of nuclear-encoded plastid proteins. Recently, it has become increasingly evident that the ubiquitin-proteasome system regulates both the import of anterograde plastid proteins and retrograde signaling from plastids to the nucleus. Targets of ubiquitin-proteasome regulation include unimported chloroplast precursor proteins in the cytosol, protein translocation machinery at the chloroplast surface, and transcription factors in the nucleus. This review will focus on the mechanism through which the ubiquitin-proteasome system optimizes plastid biogenesis and plant development through the regulation of nuclear-plastid interactions.
KW - Plastid biogenesis
KW - Plastid protein import
KW - Proteasome
KW - Retrograde signaling
KW - Ubiquitin
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U2 - 10.3389/fpls.2017.00310
DO - 10.3389/fpls.2017.00310
M3 - Review article
AN - SCOPUS:85017299179
VL - 8
JO - Frontiers in Plant Science
JF - Frontiers in Plant Science
SN - 1664-462X
M1 - 310
ER -