Two novel single nucleotide polymorphisms (SNPs) of the CYP2D6 gene in Japanese individuals.

Aiko Ebisawa; Masahiro Hiratsuka; Kanako Sakuyama; Yumiko Konno; Takamitsu Sasaki; Michinao Mizugaki

doi:10.2133/dmpk.20.294

Two novel single nucleotide polymorphisms (SNPs) of the CYP2D6 gene in Japanese individuals.

Aiko Ebisawa, Masahiro Hiratsuka, Kanako Sakuyama, Yumiko Konno, Takamitsu Sasaki, Michinao Mizugaki

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

We analyzed all the exons and exon-intron junctions of the CYP2D6 gene from 286 Japanese individuals. We detected two novel single nucleotide polymorphisms (SNPs) 2556C>T in exon 5 (Thr261Ile) and 3835A>C in exon 8 (Lys404Gln). Both these SNPs showed a frequency of 0.002.

Original language	English
Pages (from-to)	294-299
Number of pages	6
Journal	Drug metabolism and pharmacokinetics
Volume	20
Issue number	4
DOIs	https://doi.org/10.2133/dmpk.20.294
Publication status	Published - 2005 Aug
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmaceutical Science
Pharmacology (medical)

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abstract = "We analyzed all the exons and exon-intron junctions of the CYP2D6 gene from 286 Japanese individuals. We detected two novel single nucleotide polymorphisms (SNPs) 2556C>T in exon 5 (Thr261Ile) and 3835A>C in exon 8 (Lys404Gln). Both these SNPs showed a frequency of 0.002.",

author = "Aiko Ebisawa and Masahiro Hiratsuka and Kanako Sakuyama and Yumiko Konno and Takamitsu Sasaki and Michinao Mizugaki",

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AU - Ebisawa, Aiko

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AU - Sasaki, Takamitsu

AU - Mizugaki, Michinao

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AB - We analyzed all the exons and exon-intron junctions of the CYP2D6 gene from 286 Japanese individuals. We detected two novel single nucleotide polymorphisms (SNPs) 2556C>T in exon 5 (Thr261Ile) and 3835A>C in exon 8 (Lys404Gln). Both these SNPs showed a frequency of 0.002.

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Two novel single nucleotide polymorphisms (SNPs) of the CYP2D6 gene in Japanese individuals.

Abstract

ASJC Scopus subject areas

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