TY - JOUR
T1 - Two Japanese cases of anti-MOG antibody-associated encephalitis that mimicked neuro-Behçet's disease
AU - Fujimori, Juichi
AU - Takahashi, Toshiyuki
AU - Matsumoto, Yuki
AU - Fujihara, K.
AU - Takai, Yoshiki
AU - Misu, Tatsuro
AU - Nakashima, Ichiro
N1 - Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/9/15
Y1 - 2019/9/15
N2 - Recently, we documented two Japanese cases of myelin-oligodendrocyte glycoprotein (MOG) antibody-associated relapsing encephalitis among patients who had been diagnosed with probable neuro-Behçet's disease (NBD). They presented partial systemic BD symptoms, brainstem lesions, and the human leukocyte antigen (HLA) B51 allele and responded well to steroid therapy. Our cases suggest that we need to differentiate anti-MOG antibody-associated encephalitis from probable NBD because both disorders can present with brainstem or cerebral lesions, CSF pleocytosis, and elevated levels of CSF IL-6 and respond to steroid treatment. Furthermore, oral ulceration, skin lesions, and HLA-B51 might be observed nonspecifically in patients with anti-MOG antibody-associated encephalitis.
AB - Recently, we documented two Japanese cases of myelin-oligodendrocyte glycoprotein (MOG) antibody-associated relapsing encephalitis among patients who had been diagnosed with probable neuro-Behçet's disease (NBD). They presented partial systemic BD symptoms, brainstem lesions, and the human leukocyte antigen (HLA) B51 allele and responded well to steroid therapy. Our cases suggest that we need to differentiate anti-MOG antibody-associated encephalitis from probable NBD because both disorders can present with brainstem or cerebral lesions, CSF pleocytosis, and elevated levels of CSF IL-6 and respond to steroid treatment. Furthermore, oral ulceration, skin lesions, and HLA-B51 might be observed nonspecifically in patients with anti-MOG antibody-associated encephalitis.
KW - Differential diagnosis
KW - Encephalitis
KW - Myelin-oligodendrocyte glycoprotein
KW - Neuro-Behçet's disease
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U2 - 10.1016/j.jneuroim.2019.577002
DO - 10.1016/j.jneuroim.2019.577002
M3 - Article
C2 - 31279093
AN - SCOPUS:85068263492
VL - 334
JO - Advances in Neuroimmunology
JF - Advances in Neuroimmunology
SN - 0165-5728
M1 - 577002
ER -