Abstract
Octadecyl substituted amphiphiles of the four nucleobases, adenine, cytosine, guaine, and thymine (C18-Ade, C18-Cyt, C18-Gua, and C18-Thy, respectively), were prepared. Binary mixtures of these amphiphiles were spread on water surface as monolayer assemblies. Pressure-area isotherms of all pairwise combination of the nucleobase amphiphiles indicate that the Watson-Crick type base-pairings and base-stacking can stabilize monolayers at the air-water interface. Unexpected stabilization was observed in the combination of C18-Gua and C18-Thy, which resembles a "wobble" pair in RNA. Langmuir-Blodgett films were prepared on gold substrates for FT-IR measurement of the complementary hydrogen bonding between the nucleobase amphiphiles.
Original language | English |
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Pages (from-to) | 379-382 |
Number of pages | 4 |
Journal | Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals |
Volume | 371 |
DOIs | |
Publication status | Published - 2001 Jan 1 |
Keywords
- "Wobble" base-pair
- Hydrogen bond, base-stacking
- Molecular recognition
- Monolayer
- Watson-Crick type base-pair
ASJC Scopus subject areas
- Condensed Matter Physics