Abstract
(Diagram presented) Ciguatoxins, principal causative toxins of ciguatera seafood poisoning, are large ladderlike polycyclic ethers. Here, we report two convergent routes to synthesis of the multiolefinic left half of ciguatoxins based on a newly developed acyl radical strategy. Remarkably, only 13 steps from the monocyclic E-ring were required to construct the left wing.
Original language | English |
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Pages (from-to) | 5805-5808 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 8 |
Issue number | 25 |
DOIs | |
Publication status | Published - 2006 Dec 7 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry