Two cases of radiation-induced sarcoma after radiation therapy in nasopharyngeal carcinoma

Akira Okoshi, Kiyoto Shiga, Kazuha Sasaki, Yukinori Asada, Hitosni Nishikawa, Toshimitsu Kobayashi, Mika Watanabe

Research output: Contribution to journalArticle

Abstract

We report two cases of radiation-induced sarcoma after chemoradiation therapy in nasopharyngeal carcinoma. Case 1 : A 40-year-old man developed a malignant peripheral nerve sheath tumor (MPNST) in the posterior floor of the nasal cavity 10 years after treatment for nasopharyngeal cancer. Case 2 : A 64 year-old man developed a malignant fibrous histiocytoma (MFH) of the lower gum 10 years after treatment of nasopharyngeal cancer. Despite radical surgery, the man with MPNST had a recurrent tumor and died of the disease.

Original languageEnglish
Pages (from-to)533-536
Number of pages4
JournalJournal of Otolaryngology of Japan
Volume111
Issue number7
DOIs
Publication statusPublished - 2008 Jul

Keywords

  • Nasopharyngeal carcinoma
  • Radiation-induced sarcoma
  • Radical surgery

ASJC Scopus subject areas

  • Otorhinolaryngology

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