Cytomegalovirus (CMV) retinitis was detected in a 71-year-old male under systemic corticosteroid treatment for pulmonary fibrosis and in a 7-year-old boy under chemotherapy for neuroblastoma. Retinitis with extensive hemorrhage and exudates was the chief eye manifestation. The lesions responded well to systemic ganciclovir and anti CMV human monoclonal antibody. The first case showed CMV in the vitreous specimen by polymerase chain reaction. The second case showed CMV in the urine and mucous material from the pharynx. We advocate early diagnosis and treatment of CMV retinitis in immunocompromised patients before progression of retinal necrosis.
|Number of pages||5|
|Journal||Japanese Journal of Clinical Ophthalmology|
|Publication status||Published - 1995|
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