Two cases of bilateral lung transplantation combined with intracardiac repair and pulmonary artery replacement: perioperative managements based on the left ventricular function

Hiroaki Toyama, Kazutomo Saitoh, Yusuke Takei, Yutaka Ejima, Shin Kurosawa, Masanori Yamauchi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report on two patients who underwent bilateral lung transplantation (BLTx) combined with cardiac surgery. Patient 1 was a female whose pulmonary hypertension resulted from a congenital atrial septal defect (ASD) and idiopathic pulmonary arterial hypertension. She had a very small left ventricle (LV). We initiated venoarterial extracorporeal membrane oxygenation (ECMO) before induction of general anesthesia. She underwent ASD patch closure, pulmonary artery replacement, and BLTx under cardiopulmonary bypass (CPB). At the weaning from CPB, primary graft dysfunction and pulmonary edema induced by LV diastolic dysfunction was apparent. We gradually decreased the ECMO support and eventually weaned off the ECMO on the 4th postoperative day (POD) and the ventilator on the 29th POD. Patient 2 was a male with Eisenmenger syndrome, which resulted from ASD and ventricular septal defect (VSD). He had a normal LV. General anesthesia was induced smoothly without ECMO. He underwent ASD and VSD patch closure, pulmonary artery replacement, and BLTx under CPB. Weaning from CPB proceeded smoothly. These patients needed different management because of their different LV function. Especially, perioperative management of the BLTx patient with LV diastolic dysfunction was difficult. Assessment of perioperative cardiac function is very important in BLTx combined with cardiac surgery.

Original languageEnglish
Pages (from-to)957-961
Number of pages5
JournalJournal of Anesthesia
Volume29
Issue number6
DOIs
Publication statusPublished - 2015 Dec 1

Keywords

  • Bilateral lung transplantation
  • Eisenmenger syndrome
  • Intracardiac repair
  • Left ventricular diastolic dysfunction
  • Pulmonary artery replacement

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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