Triterpene saponins from the roots of Acacia albida Del. (Mimosaceae)

Abdou Tchoukoua, Turibio Kuiate Tabopda, Shota Uesugi, Misa Ohno, Ken ichi Kimura, Eunsang Kwon, Hiroyuki Momma, Ibrahim Horo, Özgen Alankuş Çalişkan, Yoshihito Shiono, Bonaventure Tchaleu Ngadjui

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Seven previously undescribed bidesmosidic triterpenoid saponins named albidosides A – G, were isolated from a methanol extract of the roots of Acacia albida. Their structures were elucidated using 1D and 2D NMR spectroscopy and mass spectrometry and determined to be bidesmosides of oleanolic acid and of 16α-hydroxyoleanolic acid. Albidosides B – G were assayed for their cytotoxicity against HeLa and HL60 cells using MTT method and microscopic observation.

Original languageEnglish
Pages (from-to)31-38
Number of pages8
JournalPhytochemistry
Volume136
DOIs
Publication statusPublished - 2017 Apr 1

Keywords

  • Acacia albida
  • Cytotoxicity
  • Mimosaceae
  • Triterpene saponins

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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