Triplet pulse seqence for superior microbubble/tissue contrast

Shin Ichiro Umemura, Takashi Azuma, Hiroshi Kuribara, Hiroshi Kanda

Research output: Contribution to journalConference articlepeer-review

7 Citations (Scopus)


A triplet pulse sequence is proposed for imaging with superior microbubble/tissue selectivity. This sequence utilizes the difference in nonlinearity between the nonlinear propagation in tissue and the nonlinear scattering by microbubbles. Three-time transmit/receive are performed with transmit pulses having the same envelope and a phase shift by 120°, and the received echo signals are summed. Numerical analysis of the microbubble scattering and the propagation in tissue predicted the selectivity superior to the conventional pulse inversion sequence by more than 20 dB in an ideal case. An experiment using a prototype scanner with a Doppler flow phantom and a contrast agent demonstrated an improvement in the selectivity by 15 dB at a typical acoustic amplitude in B-mode imaging at 2 MHz.

Original languageEnglish
Pages (from-to)429-432
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Publication statusPublished - 2003 Dec 1
Event2003 IEEE Ultrasonics Symposium - Proceedings - Honolulu, HI, United States
Duration: 2003 Oct 52003 Oct 8

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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